55201

Tocris Bioscience™ Echinomycin

Manufacturer: Tocris Bioscience™

CAS Number: 512-64-1

Select a Size

Pack Size SKU Availability Price
Each of 1 55201-Each-of-1 In Stock ₹ 15,494.92

55201 - Each of 1

₹ 15,494.92

In Stock

Quantity

1

Base Price: ₹ 15,494.92

GST (18%): ₹ 2,789.086

Total Price: ₹ 18,284.006

Chemical Name or Material

Echinomycin

Synonym

N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl-L-valine-(81)-lactone-cyclic (37)-thioether

Solubility

Soluble to 5mM in DMSO

Formula Weight

1101.26

Product Type

Bioactive Small Molecule

CAS

512-64-1

Quantity

1 mg

Molecular Formula

C51H64N12O12S2

Physical Form

Solid

Purity

>98%

Other Options

Image Product Name Manufacturer Price Range
NC1752130
Cayman Chemical Echinomycin | 512-64-1 | MFCD00156105 | 1 mg
Cayman Chemical ₹ 9,544.22
50-186-7077
Sigma Aldrich Fine Chemicals Biosciences Echinomycin >=98% (HPLC) | 512-64-1 | 1MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 15,302.41
AG16588
512-64-1 | Quinomycin A
A2B Chem ₹ 7,529.28 - ₹ 27,721.44

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Description

  • Echinomycin is a highly potent and selective HIF-1α inhibitor (IC50 = 29.4 pM)
  • Selectively inhibits HIF-1 binding to the VEGF promoter without affecting the binding of AP-1 or NF-κB
  • Inhibits colony formation of cancer stem cells (CSC) with a 100-fold selectivity over normal hematopoietic progenitor cells
  • Eradicates mouse lymphomas and human AML xenografts by eliminating CSCs.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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Tocris Bioscience™

55201

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Chemical Name or Material:
Echinomycin

Synonym:
N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl-L-valine-(81)-lactone-cyclic (37)-thioether

Solubility:
Soluble to 5mM in DMSO

Formula Weight:
1101.26

Product Type:
Bioactive Small Molecule

CAS:
512-64-1

Quantity:
1 mg

Molecular Formula:
C51H64N12O12S2

Physical Form:
Solid

Purity:
>98%

Img

Fischer Scientific

552110

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Chemical Name or Material:
3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide

Synonym:
__

Solubility:
__

Formula Weight:
347.41

Product Type:
__

CAS:
1031496-06-6

Quantity:
10 mg

Molecular Formula:
C21H21N3O2

Physical Form:
__

Purity:
>98%

Img

Fischer Scientific

552150

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Chemical Name or Material:
3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide

Synonym:
__

Solubility:
__

Formula Weight:
347.41

Product Type:
__

CAS:
1031496-06-6

Quantity:
50 mg

Molecular Formula:
C21H21N3O2

Physical Form:
__

Purity:
>98%

Img

SPEX CertiPrep

5522-AS

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Chemical Name or Material:
Free Acids Analyte Mix with Surrogate

Synonym:
__

Solubility:
__

Formula Weight:
__

Product Type:
__

CAS:
__

Quantity:
1 mL

Molecular Formula:
__

Physical Form:
__

Purity:
__