761540

Dibenzocyclooctyne-amine

for Copper-free Click Chemistry

Manufacturer: Sigma Aldrich

CAS Number: 1255942-06-3

Synonym(S): DBCO-NH2, DBCO-amine

Select a Size

Pack Size SKU Availability Price
10 MG 761540-10-MG In Stock ₹ 4,330.00
100 MG 761540-100-MG In Stock ₹ 32,951.30

761540 - 10 MG

₹ 4,330.00

In Stock

Quantity

1

Base Price: ₹ 4,330.00

GST (18%): ₹ 779.40

Total Price: ₹ 5,109.40

Quality Level

100

form

solid

reaction suitability

reaction type: click chemistryreagent type: linker

mp

86-96 °C

functional group

amine

storage temp.

−20°C

SMILES string

NCCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O

InChI

1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2

InChI key

OCCYFTDHSHTFER-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-1738-695
Sigma Aldrich Fine Chemicals Biosciences Dibenzocyclooctyne-amine | 1255942-06-3 | MFCD22380759 | 10mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 7,204.15
NC2457142
Broadpharm DBCO Amine| 1g| 1255942-06-3
Broadpharm ₹ 98,941.58
50-1738-694
Sigma Aldrich Fine Chemicals Biosciences Dibenzocyclooctyne-amine for Copper-free Click Chemistry | 1255942-06-3 | MFCD22380759 | 100MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 51,644.02
NC2046189
eMolecules​ DBCO amine | 1255942-06-3 | MFCD22380759 | 100mg
eMolecules​ ₹ 48,994.22
AR000OM0
1-Propanone, 3-amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-
Aaron Chemicals LLC ₹ 3,593.52 - ₹ 66,651.24
CS-W000423
DBCO-amine
ChemScene ₹ 7,015.92 - ₹ 1,79,676.00
AA30796
1255942-06-3 | DBCO-amine
A2B Chem ₹ 4,962.48 - ₹ 89,153.52

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Description

  • General description: Dibenzocyclooctyne-amine (DBCO-NH2), is a heterobifunctional linker containing a DBCO moiety commonly used for the site-specific functionalization of nanobodies, enabling the addition of reactive DBCO groups for subsequent click chemistry reactions.[1]
  • Application: Dibenzocyclooctyne-amine can be used as a :Linker to link azide-containing functional groups. It facilitates the formation of linkages through Strain-promoted azide-alkyne cycloaddition reactions (SPAAC)[2]Reagent in the synthesis of N-heterocyclic carbene metal thiolates. It functionalizes the metal complexes and increases their reactivity in the strain-promoted alkyne–azide cycloaddition (SPAAC) reactions[3]Amine functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

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Sigma Aldrich

761540

for Copper-free Click Chemistry...


Quality Level:
100

form:
solid

reaction suitability:
reaction type: click chemistryreagent type: linker

mp:
86-96 °C

functional group:
amine

storage temp.:
−20°C

SMILES string:
NCCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O

InChI:
1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2

InChI key:
OCCYFTDHSHTFER-UHFFFAOYSA-N

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Quality Level:
100

form:
powder

reaction suitability:
__

mp:
171 °C

functional group:
__

storage temp.:
−20°C

SMILES string:
N[C@@H](C[C@@H](O)C(O)=O)C(O)=O

InChI:
1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1

InChI key:
HBDWQSHEVMSFGY-STHAYSLISA-N

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Sigma Aldrich

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Quality Level:
100

form:
powder

reaction suitability:
__

mp:
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__

storage temp.:
−20°C

SMILES string:
N[C@@H](C[C@@H](O)C(O)=O)C(O)=O

InChI:
1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1

InChI key:
__

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Quality Level:
__

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__

reaction suitability:
__

mp:
__

functional group:
__

storage temp.:
__

SMILES string:
__

InChI:
__

InChI key:
__