930792
3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione
≥95.0%
Manufacturer: Sigma Aldrich
CAS Number: 2207541-23-7
Synonym(S): 2,6-Piperidinedione, 3-[1,3-dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 930792-50-MG | In Stock | ₹ 16,850.00 |
930792 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 16,850.00
GST (18%): ₹ 3,033.00
Total Price: ₹ 19,883.00
Quality Level
100
Assay
≥95.0%
form
powder
functional group
hydroxyl
storage temp.
2-8°C
SMILES string
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCO)C3C2)CC1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 2207541-23-7 | Phthalimidinoglutarimide-propargyl-C1-OH | A2B Chem | ₹ 26,951.40 - ₹ 2,19,461.40 |
Related Products
Description
- Application: 3-[1,3-Dihydro-4-(4-hydroxy-1-butyn-1-yl)-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione is a functionalized cereblon (CRBN) ligand used in the development of lenalidomide-based protein degrader building blocks. Can be activated by many nucleophiles or form ether linkages through its terminal hydroxyl group. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
- Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥95.0%
form: powder
functional group: hydroxyl
storage temp.: 2-8°C
SMILES string: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCO)C3C2)CC1
Quality Level:
100
Assay:
≥95.0%
form:
powder
functional group:
hydroxyl
storage temp.:
2-8°C
SMILES string:
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCO)C3C2)CC1
Quality Level: 100
Assay: ≥95.0%
form: powder
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: O=C(O)CCCCCC#CC1=CC=CC=2C(=O)N(CC12)C3C(=O)NC(=O)CC3
Quality Level:
100
Assay:
≥95.0%
form:
powder
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
O=C(O)CCCCCC#CC1=CC=CC=2C(=O)N(CC12)C3C(=O)NC(=O)CC3
Quality Level: 100
Assay: __
form: __
functional group: __
storage temp.: 2-30°C
SMILES string: OS(O)(=O)=O.Nc1ccc(N)c(Cl)c1
Quality Level:
100
Assay:
__
form:
__
functional group:
__
storage temp.:
2-30°C
SMILES string:
OS(O)(=O)=O.Nc1ccc(N)c(Cl)c1
Quality Level: 100
Assay: ≥95.0%
form: powder
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: __
Quality Level:
100
Assay:
≥95.0%
form:
powder
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
__