361798

Lithium diisopropylamide solution

2.0 M in THF/heptane/ethylbenzene

Manufacturer: Sigma Aldrich

CAS Number: 4111-54-0

Synonym(S): LDA

Select a Size

Pack Size SKU Availability Price
100 ML 361798-100-ML In Stock ₹ 8,194.53
4 X 25 ML 361798-4-X-25-ML In Stock ₹ 10,770.88
4 X 100 ML 361798-4-X-100-ML In Stock ₹ 30,039.38
800 ML 361798-800-ML In Stock ₹ 38,331.33

361798 - 100 ML

₹ 8,194.53

In Stock

Quantity

1

Base Price: ₹ 8,194.53

GST (18%): ₹ 1,475.015

Total Price: ₹ 9,669.545

form

liquid

Quality Level

200

concentration

2.0 M in THF/heptane/ethylbenzene

impurities

3 wt. % diisopropylamine

density

0.812 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

[Li]N(C(C)C)C(C)C

InChI

1S/C6H14N.Li/c1-5(2)7-6(3)4;/h5-6H,1-4H3;/q-1;+1

InChI key

ZCSHNCUQKCANBX-UHFFFAOYSA-N

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Description

  • General description: Lithium diisopropylamide solution (LDA) is a sterically hindered non-nucleophilic strong base widely used in organic synthesis.[1]
  • Application: Lithium diisopropylamide solution (LDA) can be used:As an initiator in the anionic polymerization of D,L-lactide and methyl methacrylate.[1]To facilitate ester enolization.[2]To convert carboxylic acids to enediolate intermediates for preparing trifluoromethyl ketones.[3]In ortho-lithiation of arylsulfonyloxazolidinones to prepare N-substituted saccharin analogs.[4]To catalyze ortholithiation and Fries rearrangement of aryl carbamates.[5]As a promoter in the isomerization of allylic ethers to (Z)-propenyl ethers.[6]
  • Packaging: The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.
  • Legal Information: Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

SAFETY INFORMATION

Pictograms

GHS02,GHS08,GHS05,GHS07,GHS09

Signal Word

Danger

Hazard Statements

H225,H304,H314,H335,H336,H351,H373,H410

Precautionary Statements

P210 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT RE 2 - STOT SE 3

Target Organs

Central nervous system, hearing organs, Respiratory system

Supplementary Hazards

EUH014,EUH019

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

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SMILES string:
[Li]N(C(C)C)C(C)C

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1S/C6H14N.Li/c1-5(2)7-6(3)4;/h5-6H,1-4H3;/q-1;+1

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ZCSHNCUQKCANBX-UHFFFAOYSA-N

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