50-257-6136
Invitrogen™ CYP2C9 BACULOSOMES™ Plus Reagent, rHuman
Manufacturer: Invitrogen™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-257-6136-Each-of-1 | In Stock | ₹ 24,812.40 |
50-257-6136 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,812.40
GST (18%): ₹ 4,466.232
Total Price: ₹ 29,278.632
Host Species
Human
Shipping Condition
Dry Ice
Product Type
Reagent
Product Line
BACULOSOMES™
Content And Storage
-80°C
Quantity
0.5 nmol
Research Category
Toxicology and Drug Metabolism
Related Products
Description
- Cytochrome P450 BACULOSOMES™ Plus Reagents are microsomes prepared from insect cells infected with recombinant baculovirus containing a human CYP450 isozyme, as well as human cytochrome P450 reductase
- For this particular isozyme (CYP2C9), human cytochrome b5 is also included
- Single human P450 isozyme for detailed drug metabolism studies High specific activity increases dynamic range and sensitivity No background metabolism for clear results Single Overexpressed Human CYP450 Isozyme CYP450 BACULOSOMES™ Plus Reagents offer a distinct advantage over Human Liver Microsomes (HLMs) in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s or other classes of drug metabolizing enzymes
- High Activity Results in Increased Sensitivity Compound rankings based on metabolism and inhibition profiles observed with CYP450 BACULOSOMES™ Plus Reagents are very similar to those seen with HLMs for most compounds tested
- However, CYP450 BACULOSOMES™ Plus Reagents activity and metabolic rates with most substrates is significantly higher than those seen with HLMs
- This results in a broad dynamic range and high sensitivity in assays utilizing CYP450 BACULOSOMES™ Plus Reagents
- The high level of activity and reproducibility of the enzyme component observed in the reaction with most probe substrates makes CYP450 BACULOSOMES™ Plus Reagents well suited to high-throughput screening formats
- High Signal to Noise Ratio No background metabolism by endogenous insect CYP450s has been detected with any of the Vivid™ probe substrates tested so far
- Applications: isozyme identification, DMPK analysis, isozyme-specific metabolism, and inhibition screening For Research Use Only
- Not for any animal or human therapeutic or diagnostic use.
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Host Species: Human
Shipping Condition: Dry Ice
Product Type: Reagent
Product Line: BACULOSOMES™
Content And Storage: -80°C
Quantity: 0.5 nmol
Research Category: Toxicology and Drug Metabolism
Host Species:
Human
Shipping Condition:
Dry Ice
Product Type:
Reagent
Product Line:
BACULOSOMES™
Content And Storage:
-80°C
Quantity:
0.5 nmol
Research Category:
Toxicology and Drug Metabolism
Host Species: __
Shipping Condition: Dry Ice
Product Type: FRET Assay Kit
Product Line: __
Content And Storage: Components of the BACE1 FRET Assay Kit are listed in Table 1. Sufficient reagent is supplied for 400 high-throughput kinetic or endpoint assays. The BACE1 Enzyme is also available separately. Store BACE1 Enzyme at -80°C. Store BACE1 Substrate and BACE1 Product Standard at -20°C. Avoid subjecting these components to repeated freeze-thaw cycles. The BACE1 Assay Buffer and BACE1 Stop Solution can be thawed upon receipt and stored at room temperature.
Quantity: 400 x 40 μL Assays
Research Category: __
Host Species:
__
Shipping Condition:
Dry Ice
Product Type:
FRET Assay Kit
Product Line:
__
Content And Storage:
Components of the BACE1 FRET Assay Kit are listed in Table 1. Sufficient reagent is supplied for 400 high-throughput kinetic or endpoint assays. The BACE1 Enzyme is also available separately. Store BACE1 Enzyme at -80°C. Store BACE1 Substrate and BACE1 Product Standard at -20°C. Avoid subjecting these components to repeated freeze-thaw cycles. The BACE1 Assay Buffer and BACE1 Stop Solution can be thawed upon receipt and stored at room temperature.
Quantity:
400 x 40 μL Assays
Research Category:
__
Host Species: __
Shipping Condition: Approved for shipment on Wet or Dry Ice
Product Type: __
Product Line: VIVID™
Content And Storage: Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)
Quantity: 0.1 mg
Research Category: __
Host Species:
__
Shipping Condition:
Approved for shipment on Wet or Dry Ice
Product Type:
__
Product Line:
VIVID™
Content And Storage:
Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)
Quantity:
0.1 mg
Research Category:
__
Host Species: __
Shipping Condition: Approved for shipment at Room Temperature or on Wet or Dry Ice
Product Type: Nuclear Receptor Buffer
Product Line: __
Content And Storage: Nuclear Receptor Buffer F may be shipped frozen or at room temperature. It should be stored at room temperature (20-30°C).
Quantity: 25 mL
Research Category: __
Host Species:
__
Shipping Condition:
Approved for shipment at Room Temperature or on Wet or Dry Ice
Product Type:
Nuclear Receptor Buffer
Product Line:
__
Content And Storage:
Nuclear Receptor Buffer F may be shipped frozen or at room temperature. It should be stored at room temperature (20-30°C).
Quantity:
25 mL
Research Category:
__