50-257-6138
Thermo Scientific™ Vivid™ EOMCC Substrate
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-257-6138-Each-of-1 | In Stock | ₹ 16,341.96 |
50-257-6138 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,341.96
GST (18%): ₹ 2,941.553
Total Price: ₹ 19,283.513
Content And Storage
Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)
Product Line
VIVID™
Substrate
EOMCC
Substrate Type
Cytochrome P450 Substrate
Detection Method
Fluorescence
Quantity
0.1 mg
Substrate Properties
Chemical Substrate
Shipping Condition
Approved for shipment on Wet or Dry Ice
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Description
- Vivid™ Substrates are blocked dyes that yield a minimal fluorescence signal until oxidation occurs
- Cytochrome P450 metabolism at either of two potential oxidation sites releases the highly fluorescent product
- They have superior fluorescence, solubility, and kinetic properties compared to conventional fluorogenic probes
- This results in higher sensitivity, greater signal-to-noise ratio, and better assay reproducibility
- When used in combination with CYP450 BACULOSOMES™ Plus Reagents as part of the Vivid™ CYP450 Screening Kits, the Vivid™ Substrates enable rapid, robust detection of cytochrome P450 inhibitors
- This particular substrate (Vivid ™ EOMCC Substrate) yields a product that emits a blue fluorescence
- More About Vivid™ CYP450 Screening Kits Vivid™ CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition
- Vivid™ CYP450 Screening Kits include Vivid™ Substrate, Vivid™ Fluorescent Standard, reaction buffer, Vivid™ Regeneration System, NADP+, and CYP450 BACULOSOMES™ Plus Reagent
- CYP450 BACULOSOMES™ Plus Reagents are microsomes prepared from insect cells expressing a human CYP450 isozyme and human cytochrome P450 reductase
- CYP450 BACULOSOMES™ Plus Reagents offer a distinct advantage over human liver microsomes in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s
- Applications High-throughput screening of enzyme-drug interactions Compound profiling for drug inhibition of cytochrome P450 isozymes Generation of predictive SAR models to guide compound acquisition
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Content And Storage: Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)
Product Line: VIVID™
Substrate: EOMCC
Substrate Type: Cytochrome P450 Substrate
Detection Method: Fluorescence
Quantity: 0.1 mg
Substrate Properties: Chemical Substrate
Shipping Condition: Approved for shipment on Wet or Dry Ice
Content And Storage:
Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)
Product Line:
VIVID™
Substrate:
EOMCC
Substrate Type:
Cytochrome P450 Substrate
Detection Method:
Fluorescence
Quantity:
0.1 mg
Substrate Properties:
Chemical Substrate
Shipping Condition:
Approved for shipment on Wet or Dry Ice
Content And Storage: Nuclear Receptor Buffer F may be shipped frozen or at room temperature. It should be stored at room temperature (20-30°C).
Product Line: __
Substrate: __
Substrate Type: __
Detection Method: __
Quantity: 25 mL
Substrate Properties: __
Shipping Condition: Approved for shipment at Room Temperature or on Wet or Dry Ice
Content And Storage:
Nuclear Receptor Buffer F may be shipped frozen or at room temperature. It should be stored at room temperature (20-30°C).
Product Line:
__
Substrate:
__
Substrate Type:
__
Detection Method:
__
Quantity:
25 mL
Substrate Properties:
__
Shipping Condition:
Approved for shipment at Room Temperature or on Wet or Dry Ice
Content And Storage: The Eu-Streptavidin Kit contains 10 μg Eu-streptavidin, 400 μl AlexaFluor™ 647-biotin control peptide and 100 mL of TR-FRET Dilution Buffer. Store reagents as indicated on the certificate of analysis.
Product Line: LanthaScreen™
Substrate: __
Substrate Type: __
Detection Method: __
Quantity: 1 kit
Substrate Properties: __
Shipping Condition: Dry Ice
Content And Storage:
The Eu-Streptavidin Kit contains 10 μg Eu-streptavidin, 400 μl AlexaFluor™ 647-biotin control peptide and 100 mL of TR-FRET Dilution Buffer. Store reagents as indicated on the certificate of analysis.
Product Line:
LanthaScreen™
Substrate:
__
Substrate Type:
__
Detection Method:
__
Quantity:
1 kit
Substrate Properties:
__
Shipping Condition:
Dry Ice
Content And Storage: Store at -20°C.
Product Line: __
Substrate: __
Substrate Type: __
Detection Method: __
Quantity: 25 μL
Substrate Properties: __
Shipping Condition: Dry Ice
Content And Storage:
Store at -20°C.
Product Line:
__
Substrate:
__
Substrate Type:
__
Detection Method:
__
Quantity:
25 μL
Substrate Properties:
__
Shipping Condition:
Dry Ice