P2974

Thermo Scientific™ Vivid™ DBOMF Substrate

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 P2974-Each-of-1 In Stock ₹ 15,999.72

P2974 - Each of 1

₹ 15,999.72

In Stock

Quantity

1

Base Price: ₹ 15,999.72

GST (18%): ₹ 2,879.95

Total Price: ₹ 18,879.67

Content And Storage

Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Form

Liquid

Quantity

0.1 mg

Substrate Properties

Chemical Substrate

Shipping Condition

Approved for shipment on Wet or Dry Ice

Detection Method

Fluorescence

Product Line

VIVID™

Substrate

DBOMF

Substrate Type

Cytochrome P450 Substrate

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Description

  • Vivid™ Substrates are blocked dyes that yield a minimal fluorescence signal until oxidation occurs
  • Cytochrome P450 metabolism at either of two potential oxidation sites releases the highly fluorescent product
  • They have superior fluorescence, solubility, and kinetic properties compared to conventional fluorogenic probes
  • This results in higher sensitivity, greater signal-to-noise ratio, and better assay reproducibility
  • When used in combination with CYP450 BACULOSOMES™ Plus Reagents as part of the Vivid™ CYP450 Screening Kits, the Vivid™ Substrates enable rapid, robust detection of cytochrome P450 inhibitors
  • This particular substrate (Vivid ™ DBOMF Substrate) yields a product that emits a green fluorescence
  • More About Vivid™ CYP450 Screening Kits Vivid™ CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition
  • Vivid™ CYP450 Screening Kits include Vivid™ Substrate, Vivid™ Fluorescent Standard, reaction buffer, Vivid™ Regeneration System, NADP+, and CYP450 BACULOSOMES™ Plus Reagent
  • CYP450 BACULOSOMES™ Plus Reagents are microsomes prepared from insect cells expressing a human CYP450 isozyme and human cytochrome P450 reductase
  • CYP450 BACULOSOMES™ Plus Reagents offer a distinct advantage over human liver microsomes in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s
  • Applications High-throughput screening of enzyme-drug interactions Compound profiling for drug inhibition of cytochrome P450 isozymes Generation of predictive SAR models to guide compound acquisition

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Fischer Scientific

P2974

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Content And Storage:
Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Form:
Liquid

Quantity:
0.1 mg

Substrate Properties:
Chemical Substrate

Shipping Condition:
Approved for shipment on Wet or Dry Ice

Detection Method:
Fluorescence

Product Line:
VIVID™

Substrate:
DBOMF

Substrate Type:
Cytochrome P450 Substrate

Img

Fischer Scientific

P2975

--


Content And Storage:
Vivid™ CYP450 Screening kits include Vivid™ CYP450 Fluorogenic substrates, BACULOSOMES™ CYP450 reagents, fluorescent standards, and an NADPH-regeneration system. Vivid™ CYP450 Fluorogenic substrates are also available separately. Store reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Form:
__

Quantity:
0.1mg

Substrate Properties:
Chemical Substrate

Shipping Condition:
Approved for shipment on Wet or Dry Ice

Detection Method:
Fluorescence

Product Line:
VIVID™

Substrate:
BOMCC

Substrate Type:
Cytochrome P450 Substrate

Img

Fischer Scientific

P2979

--


Content And Storage:
Vivid™ CYP450 Screening kits include:• Vivid™ CYP450 Fluorogenic substrates (also available separately)• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration systemStore reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Form:
__

Quantity:
1 mg

Substrate Properties:
Chemical Substrate

Shipping Condition:
Approved for shipment on Wet or Dry Ice

Detection Method:
Fluorescence

Product Line:
VIVID™

Substrate:
DBOMF

Substrate Type:
Cytochrome P450 Substrate

Img

Fischer Scientific

P2980

--


Content And Storage:
Vivid™ CYP450 Screening kits include Vivid™ CYP450 Fluorogenic substrates, BACULOSOMES™ CYP450 reagents, fluorescent standards, and an NADPH-regeneration system. Vivid™ CYP450 Fluorogenic substrates are also available separately. Store reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Form:
__

Quantity:
1mg

Substrate Properties:
Chemical Substrate

Shipping Condition:
Approved for shipment on Wet or Dry Ice

Detection Method:
Fluorescence

Product Line:
VIVID™

Substrate:
BOMCC

Substrate Type:
Cytochrome P450 Substrate