764736

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)-block-decane

PEG average Mn 2,000, PDLLA average Mn 2,000

Manufacturer: Sigma Aldrich

Synonym(S): PEG-PDLLA-decane, PEG-b-PLA-b-decane, PEG-PLA

Select a Size

Pack Size SKU Availability Price
1 G 764736-1-G In Stock ₹ 45,165.90

764736 - 1 G

₹ 45,165.90

In Stock

Quantity

1

Base Price: ₹ 45,165.90

GST (18%): ₹ 8,129.862

Total Price: ₹ 53,295.762

form

pellets

Quality Level

100

mol wt

PDLLA average Mn 2,000PEG average Mn 2,000average Mn 4,000 (total)

degradation timeframe

2-5 weeks

transition temp

Tm 29-33 °C

PDI

<1.1 (typical PEG)<1.2<1.3 (overall)

storage temp.

2-8°C

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Description

  • General description: Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as a carrier for hydrophobic drugs like Paclitaxel. The hydrophilic PEG and hydrophobic PDLLA form the micelle core wherein the hydrophobic drug is loaded. The incorporation of the 10-alkyl end cap (decane) increases the hydrophobicity of the micelle core and increases its solubilizing capability for hydrophobic drugs.†
  • Application: Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.[1]
  • Features and Benefits: Good biocompatibility, low immunogenicity and good degradability.Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.[2]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

>230.0 °F

Flash Point(C)

> 110 °C

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Show Difference

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Sigma Aldrich

764736

PEG average Mn 2,000, PDLLA average...


form:
pellets

Quality Level:
100

mol wt:
PDLLA average Mn 2,000PEG average Mn 2,000average Mn 4,000 (total)

degradation timeframe:
2-5 weeks

transition temp:
Tm 29-33 °C

PDI:
<1.1 (typical PEG)<1.2<1.3 (overall)

storage temp.:
2-8°C

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pellets

Quality Level:
100

mol wt:
PEG average Mn 2,000PLGA average Mn 11,500average Mn 13,500 (total)

degradation timeframe:
1-4 weeks

transition temp:
Tm 298-303 °CTg 40 °C (PDLLA block)Tg 6 °C (PEG block)

PDI:
≤2.0

storage temp.:
2-8°C

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form:
semisolid

Quality Level:
100

mol wt:
PEG average Mn 1,000PLGA average Mn 2,200average Mn (1100-1000-1100)

degradation timeframe:
2-3 weeks

transition temp:
Tm 230-235 °C

PDI:
<2.0

storage temp.:
2-8°C

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mol wt:
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degradation timeframe:
1-4 weeks

transition temp:
Tm 241-246 °C

PDI:
≤2.0

storage temp.:
2-8°C