764817

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

average Mn (1100-1000-1100), lactide:glycolide 75:25

Manufacturer: Sigma Aldrich

Synonym(S): PLGA-PEG-PLGA

Select a Size

Pack Size SKU Availability Price
1 G 764817-1-G In Stock ₹ 41,514.00

764817 - 1 G

₹ 41,514.00

In Stock

Quantity

1

Base Price: ₹ 41,514.00

GST (18%): ₹ 7,472.52

Total Price: ₹ 48,986.52

description

typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS)

Quality Level

100

form

semisolid

feed ratio

lactide:glycolide 75:25

mol wt

PEG average Mn 1,000PLGA average Mn 2,200average Mn (1100-1000-1100)

degradation timeframe

2-3 weeks

transition temp

Tm 230-235 °C

PDI

<2.0

storage temp.

2-8°C

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Description

  • General description: PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.[1]
  • Application: Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.[2][3]
  • Features and Benefits: Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.[1]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Show Difference

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Sigma Aldrich

764817

average Mn (1100-1000-1100), lactid...


description:
typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS)

Quality Level:
100

form:
semisolid

feed ratio:
lactide:glycolide 75:25

mol wt:
PEG average Mn 1,000PLGA average Mn 2,200average Mn (1100-1000-1100)

degradation timeframe:
2-3 weeks

transition temp:
Tm 230-235 °C

PDI:
<2.0

storage temp.:
2-8°C

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degradation timeframe:
1-4 weeks

transition temp:
Tm 241-246 °C

PDI:
≤2.0

storage temp.:
2-8°C

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