Thermo Scientific™ DTT (dithiothreitol)

Description

• DTT (DL-Dithiothreitol; Clelands reagent) is used to stabilize enzymes and other proteins which possess free sulfhydryl groups
• It has been shown to restore activity lost by oxidation of these groups in vitro
• DTT quantitatively reduces disulfide bonds and maintains monothiols in a reduced state
• At a final 0.1 M concentration, DTT is also widely used for disruption of protein disulfide bonds in SDS-polyacrylamide gel electrophoresis
• Highlights Free of endo-, exodeoxyribonucleases, ribonucleases, and phosphatases.