560750
Tocris Bioscience™ GNF 7
Manufacturer: Fischer Scientific
CAS Number: 839706-07-9
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 560750-Each-of-1 | In Stock | ₹ 88,629.89 |
560750 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 88,629.89
GST (18%): ₹ 15,953.38
Total Price: ₹ 1,04,583.27
Chemical Name or Material
Ras GTPase Inhibitors
Quantity
50 mg
Molecular Formula
C28H24F3N7O2
Purity
>98%
CAS
839706-07-9
Target
Small G Protein Inhibitors
Formula Weight
547.53
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ GNF 7 | Fischer Scientific | -- | |
| | Tocris Bioscience™ GNF 7 | Fischer Scientific | ₹ 21,239.41 | |
 | Medchemexpress LLC HY-10943 5mg Medchemexpress, GNF-7 CAS:839706-07-9 Purity:>98% | Medchemexpress LLC | ₹ 9,702.50 | |
 | eMolecules Medchem Express / GNF-7 / 5mg / 446259574 / HY-10943 / / 839706-07-9 / MFCD18251569 / 547.542 / C28H24F3N7O2 | eMolecules | ₹ 13,602.33 | |
 | 839706-07-9 | BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)- | A2B Chem | ₹ 2,481.24 - ₹ 13,860.72 |
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Description
- GNF 7 is a potent Bcr-Abl inhibitor (IC50 values are 61 and 133 nM for T315I and wild-type Bcr-Abl, respectively), inhibiting a range of clinically relevant Bcr-Abl mutants such as T315I, G250E, E255V, F317L and M351T
- GNF 7 is also a Ras signaling inhibitor as well as inhibiting Ack1 and germinal center kinase (GCK)
- GNF 7 induces cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations, and shows growth inhibitory activity in human colon cancer cells
- It prolongs survival in a leukemia cell xenotransplantation model in mice and is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: Ras GTPase Inhibitors
Quantity: 50 mg
Molecular Formula: C28H24F3N7O2
Purity: >98%
CAS: 839706-07-9
Target: Small G Protein Inhibitors
Formula Weight: 547.53
Chemical Name or Material:
Ras GTPase Inhibitors
Quantity:
50 mg
Molecular Formula:
C28H24F3N7O2
Purity:
>98%
CAS:
839706-07-9
Target:
Small G Protein Inhibitors
Formula Weight:
547.53
Chemical Name or Material: N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
Quantity: 10 mg
Molecular Formula: C22H32N6.2HCl
Purity: >99%
CAS: 1883548-83-1
Target: Cyclin-dependent Kinase Inhibitors
Formula Weight: 453.45
Chemical Name or Material:
N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
Quantity:
10 mg
Molecular Formula:
C22H32N6.2HCl
Purity:
>99%
CAS:
1883548-83-1
Target:
Cyclin-dependent Kinase Inhibitors
Formula Weight:
453.45
Chemical Name or Material: __
Quantity: __
Molecular Formula: __
Purity: __
CAS: __
Target: __
Formula Weight: __
Chemical Name or Material:
__
Quantity:
__
Molecular Formula:
__
Purity:
__
CAS:
__
Target:
__
Formula Weight:
__
Chemical Name or Material: N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
Quantity: 50 mg
Molecular Formula: C22H32N6.2HCl
Purity: >99%
CAS: 1883548-83-1
Target: Cyclin-dependent Kinase Inhibitors
Formula Weight: 453.45
Chemical Name or Material:
N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
Quantity:
50 mg
Molecular Formula:
C22H32N6.2HCl
Purity:
>99%
CAS:
1883548-83-1
Target:
Cyclin-dependent Kinase Inhibitors
Formula Weight:
453.45