60-531-0
Tocris Bioscience™ LDN 193189 dihydrochloride
Manufacturer: Fischer Scientific
CAS Number: 1435934-00-1
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 60-531-0-Each-of-1 | In Stock | ₹ 29,192.00 |
60-531-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,192.00
GST (18%): ₹ 5,254.56
Total Price: ₹ 34,446.56
Chemical Name or Material
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Synonym
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility
Soluble to 50mM in water and to 20mM in DMSO
Molecular Formula
C25H22N60.2 HCl
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
1435934-00-1
Quantity
10 mg
Target
BMP and Other Activin Receptor Inhibitors
Formula Weight
479.4
Color
Orange
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ LDN 193189 dihydrochloride | Fischer Scientific | -- | |
| | Tocris Bioscience™ LDN 193189 dihydrochloride | Fischer Scientific | ₹ 1,10,360.00 | |
 | 1435934-00-1 | LDN 193189 hydrochloride | A2B Chem | ₹ 2,047.00 - ₹ 17,622.00 |
Related Products
Description
- LDN 193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor (IC50 values are 5 and 30 nM, respectively); inhibits BMP4-mediated Smad1/5/8 activation
- Exhibits >200-fold selectivity for BMP signaling over TGF-β signaling
- Also exhibits selectivity over AMPK, PDGFR and MAPK signaling
- Promotes neural induction of hPSCs in combination with SB 431542 (Cat.No
- 1614)
- Also induces differentiation of hPSCs into nociceptive sensory neurons in combination with SB 431542 (Cat.No
- 1614), SU 5402 (Cat.No.3300), CHIR 99021 (Cat.No
- 4423) and DAPT (Cat.No
- 2634)
- LDN 193189 synthesized to Ancillary Material Grade also available
- For more information about how LDN 193189 dihydrochloride may be used, see our protocols: Generation of β cells from hPSCs, Generating Midbrain Dopaminergic Neurons from hPSCs, Accelerated Induction of Cortical Neurons from hiPSCs .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Synonym: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility: Soluble to 50mM in water and to 20mM in DMSO
Molecular Formula: C25H22N60.2 HCl
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1435934-00-1
Quantity: 10 mg
Target: BMP and Other Activin Receptor Inhibitors
Formula Weight: 479.4
Color: Orange
Purity: 98%
Chemical Name or Material:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Synonym:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility:
Soluble to 50mM in water and to 20mM in DMSO
Molecular Formula:
C25H22N60.2 HCl
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1435934-00-1
Quantity:
10 mg
Target:
BMP and Other Activin Receptor Inhibitors
Formula Weight:
479.4
Color:
Orange
Purity:
98%
Chemical Name or Material: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Synonym: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility: Soluble to 50mM in water and to 20mM in DMSO
Molecular Formula: C25H22N60.2 HCl
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1435934-00-1
Quantity: 50 mg
Target: BMP and Other Activin Receptor Inhibitors
Formula Weight: 479.4
Color: Orange
Purity: 98%
Chemical Name or Material:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Synonym:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Solubility:
Soluble to 50mM in water and to 20mM in DMSO
Molecular Formula:
C25H22N60.2 HCl
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1435934-00-1
Quantity:
50 mg
Target:
BMP and Other Activin Receptor Inhibitors
Formula Weight:
479.4
Color:
Orange
Purity:
98%
Chemical Name or Material: 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Synonym: __
Solubility: __
Molecular Formula: C22H24N2O3
Physical Form: __
Product Type: __
CAS: 1933533-18-6
Quantity: 10 mg
Target: __
Formula Weight: Observed MW: 364.44
Color: __
Purity: __
Chemical Name or Material:
4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Synonym:
__
Solubility:
__
Molecular Formula:
C22H24N2O3
Physical Form:
__
Product Type:
__
CAS:
1933533-18-6
Quantity:
10 mg
Target:
__
Formula Weight:
Observed MW: 364.44
Color:
__
Purity:
__
Chemical Name or Material: 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Synonym: __
Solubility: __
Molecular Formula: C22H24N2O3
Physical Form: __
Product Type: __
CAS: 1933533-18-6
Quantity: 50 mg
Target: __
Formula Weight: Observed MW: 364.44
Color: __
Purity: __
Chemical Name or Material:
4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
Synonym:
__
Solubility:
__
Molecular Formula:
C22H24N2O3
Physical Form:
__
Product Type:
__
CAS:
1933533-18-6
Quantity:
50 mg
Target:
__
Formula Weight:
Observed MW: 364.44
Color:
__
Purity:
__