66-055
Tocris Bioscience™ dTAG-13
Manufacturer: Tocris Bioscience™
CAS Number: 2064175-41-1
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 66-055-Each-of-1 | In Stock | ₹ 59,335.86 |
66-055 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,335.86
GST (18%): ₹ 10,680.455
Total Price: ₹ 70,016.315
Chemical Name or Material
1-[(2 S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2 S)-2-piperidinecarboxylate (1 R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester
Quantity
5 mg
Molecular Formula
C57H68N4O15
Purity
98%
CAS
2064175-41-1
Target
TAG Degradation Platforms
Formula Weight
1049.18
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-114421 5mg , FKBP12 PROTAC dTAG-13 CAS:2064175-41-1 Purity:>98% | Medchemexpress LLC | ₹ 49,410.90 | |
 | Medchemexpress LLC FKBP12 PROTAC dTAG-13 (Synonyms: dTAG-13) | CAS No. : 2064175-41-1 | Purity: 99.75% | Medchemexpress LLC | ₹ 4,04,720.19 | |
 | 2064175-41-1 | FKBP12 PROTAC dTAG-13 | A2B Chem | ₹ 25,325.76 - ₹ 78,287.40 |
Related Products
Description
- PROTAC targeting mutant FKBP12F36V fusion proteins
- Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a cereblon-binding ligand
- FKBP12F36V can be expressed as a fusion with a target protein of interest using genome engineering techniques (via transgene expression or CRISPR-mediated locus-specific knock-in)
- Application of dTAG-13 induces rapid, reversible and selective degradation of FKBP12F36V fusion proteins in vitro and in vivo
- dTAG is generalizable to a range of fusion proteins; useful as an alternative to genetic methods for target validation
- Plasmid vectors for the lentiviral expression and CRISPR-mediated knock-in of FKBP12F36V are available from Addgene
- dTAG-13 is a degrader targeting mutant FKBP12F36V fusion proteins
- Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a cereblon-binding ligand
- Application of dTAG-13 induces rapid, reversible and selective degradation of FKBP12F36V fusion proteins in vitro and in vivo
- dTAG is generalizable to a range of fusion proteins; useful as an alternative to genetic methods for target validation
- Negative control (Cat
- No
- 6916) also available
- FKBP12F36V can be expressed as a fusion with a target protein of interest using genome engineering techniques, via transgene expression or CRISPR-mediated locus-specific knock-in
- Custom knock-in cell lines for the dTAG and aTAG platforms are available from our sister brand R&D Systems
- Email TPD@bio-techne.com to enquire
- Plasmid vectors for the lentiviral expression and CRISPR-mediated knock-in of FKBP12F36V are available from Addgene.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 1-[(2 S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2 S)-2-piperidinecarboxylate (1 R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester
Quantity: 5 mg
Molecular Formula: C57H68N4O15
Purity: 98%
CAS: 2064175-41-1
Target: TAG Degradation Platforms
Formula Weight: 1049.18
Chemical Name or Material:
1-[(2 S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2 S)-2-piperidinecarboxylate (1 R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1 H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester
Quantity:
5 mg
Molecular Formula:
C57H68N4O15
Purity:
98%
CAS:
2064175-41-1
Target:
TAG Degradation Platforms
Formula Weight:
1049.18
Chemical Name or Material: 2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide dihydrochloride
Quantity: 5 mg
Molecular Formula: C40H45N7O10.2HCl
Purity: 98%
CAS: 2341840-98-8
Target: __
Formula Weight: 856.75
Chemical Name or Material:
2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide dihydrochloride
Quantity:
5 mg
Molecular Formula:
C40H45N7O10.2HCl
Purity:
98%
CAS:
2341840-98-8
Target:
__
Formula Weight:
856.75
Chemical Name or Material: __
Quantity: 5 mg
Molecular Formula: C55H68N8O13S2
Purity: 98%
CAS: 2170695-14-2
Target: __
Formula Weight: 1113.3
Chemical Name or Material:
__
Quantity:
5 mg
Molecular Formula:
C55H68N8O13S2
Purity:
98%
CAS:
2170695-14-2
Target:
__
Formula Weight:
1113.3
Chemical Name or Material: __
Quantity: __
Molecular Formula: __
Purity: __
CAS: __
Target: __
Formula Weight: __
Chemical Name or Material:
__
Quantity:
__
Molecular Formula:
__
Purity:
__
CAS:
__
Target:
__
Formula Weight:
__