69-795-0
Tocris Bioscience™ SEN 177
Manufacturer: Fischer Scientific
CAS Number: 2117405-13-5
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 69-795-0-Each-of-1 | In Stock | ₹ 67,079.04 |
69-795-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,079.04
GST (18%): ₹ 12,074.227
Total Price: ₹ 79,153.267
Chemical Name or Material
6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Quantity
50 mg
Molecular Formula
C18H19FN6
CAS
2117405-13-5
Target
Other Transferase Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ SEN 177 | Fischer Scientific | -- | |
| | Tocris Bioscience™ SEN 177 | Fischer Scientific | ₹ 16,016.83 | |
 | 2117405-13-5 | 3-(6-FLUOROPYRIDIN-3-YL)-2-[4-(4-METHYL-4H-1,2,4-TRIAZOL-3-YL)PIPERIDIN-1-YL]PYRIDINE | A2B Chem | ₹ 3,850.20 - ₹ 30,202.68 |
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Description
- Description SEN 177 is a potent glutaminyl cyclase (QPCT) inhibitor (IC50 = 53 nM)
- SEN 177 reduces aggregation of mutant huntingtin (mHTT) through inhibition of QPCT and reduces Q80 aggregates in vitro
- Inhibition of QPCT also reduces aggregate formation in in vivo models of Huntington's disease
- SEN 177 potently inhibits QPCT-like protein (IC50 = 13 nM) and disrupts binding of SIRP-α to CD47
- The compound increases antibody-dependent cellular phagocytosis and cytotoxicity in cancer cell lines.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Quantity: 50 mg
Molecular Formula: C18H19FN6
CAS: 2117405-13-5
Target: Other Transferase Inhibitors
Purity: 0.98
Chemical Name or Material:
6 '-Fluoro-2-[4-(4-methyl-4 H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3 '-bipyridine
Quantity:
50 mg
Molecular Formula:
C18H19FN6
CAS:
2117405-13-5
Target:
Other Transferase Inhibitors
Purity:
0.98
Chemical Name or Material: 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine
Quantity: 25 mg
Molecular Formula: C26H26F3N7O2
CAS: 1227158-85-1
Target: __
Purity: 98%
Chemical Name or Material:
1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine
Quantity:
25 mg
Molecular Formula:
C26H26F3N7O2
CAS:
1227158-85-1
Target:
__
Purity:
98%
Chemical Name or Material: 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine
Quantity: 5 mg
Molecular Formula: C26H26F3N7O2
CAS: 1227158-85-1
Target: __
Purity: 98%
Chemical Name or Material:
1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine
Quantity:
5 mg
Molecular Formula:
C26H26F3N7O2
CAS:
1227158-85-1
Target:
__
Purity:
98%
Chemical Name or Material: 3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride
Quantity: 10 mg
Molecular Formula: C32H34F3N5O4.2HCl
CAS: __
Target: __
Purity: 98%
Chemical Name or Material:
3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride
Quantity:
10 mg
Molecular Formula:
C32H34F3N5O4.2HCl
CAS:
__
Target:
__
Purity:
98%