71-935-0
Tocris Bioscience™ Deschloroclozapine
Manufacturer: Fischer Scientific
CAS Number: 1977-07-07 00:00:00
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 71-935-0-Each-of-1 | In Stock | ₹ 67,996.00 |
71-935-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,996.00
GST (18%): ₹ 12,239.28
Total Price: ₹ 80,235.28
Chemical Name or Material
11-(4-Methyl-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine
Quantity
50 mg
Molecular Formula
C18H20N4
CAS
1977-07-07 00:00:00
Target
DREADD Activators
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Deschloroclozapine | Fischer Scientific | -- | |
| | Tocris Bioscience™ Deschloroclozapine | Fischer Scientific | ₹ 16,162.40 |
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Description
- Deschloroclozapine is a high affinity and highly potent activator of muscarinic DREADDs (Ki values are 6.3 nM for hM3Dq and 4.2 nM for hM4Di, in vitro ; EC50 values are 0.13 nM for hM3Dq and 0.081 nM for hM4Di, in vitro )
- Derivative of clozapine (Cat
- No
- 0444)
- Exhibits 100-fold greater affinity for hM3Dq and hM4Di compared to clozapine N -oxide (CNO; Cat
- No
- 4936), and 50-fold greater affinity compared to DREADD agonist 21 (Cat
- No
- 5548)
- Displays low 'off-target' receptor binding (Ki >100 nM at majority of GPCRs, ion channels and transporters tested)
- Displays rapid (approx
- 10 minutes after i.p injection) binding and activation of hM3Dq and hM4Di in mice and non-human primates
- Induces spatial memory deficits in non-human primates expressing hM4Di in the prefrontal cortex.
SAFETY INFORMATION
- Recommended Storage : Store at RT
Compare Similar Items
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Chemical Name or Material: 11-(4-Methyl-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine
Quantity: 50 mg
Molecular Formula: C18H20N4
CAS: 1977-07-07 00:00:00
Target: DREADD Activators
Purity: 0.98
Chemical Name or Material:
11-(4-Methyl-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine
Quantity:
50 mg
Molecular Formula:
C18H20N4
CAS:
1977-07-07 00:00:00
Target:
DREADD Activators
Purity:
0.98
Chemical Name or Material: 2,3,5-Trideoxy-N-[(1 S,2 R)-2,3-dihydro-2-hydroxy-1 H-inden-1-yl]-5-[(2 S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate
Quantity: 50 mg
Molecular Formula: C36H47N5O4.H2SO4
CAS: 157810-81-6
Target: HIV Protease Inhibitors
Purity: 0.98
Chemical Name or Material:
2,3,5-Trideoxy-N-[(1 S,2 R)-2,3-dihydro-2-hydroxy-1 H-inden-1-yl]-5-[(2 S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate
Quantity:
50 mg
Molecular Formula:
C36H47N5O4.H2SO4
CAS:
157810-81-6
Target:
HIV Protease Inhibitors
Purity:
0.98
Chemical Name or Material: __
Quantity: 200 U
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