7110930
Tocris Bioscience™ PH 797804
Potent and selective p38α/β inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1358027-80-1
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Chemical Name or Material
(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide
Target
p38 Inhibitors
Formula Weight
477.3
CAS
1358027-80-1
Molecular Formula
C22H19BrF2N2O3
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ PH 797804 | Fischer Scientific | ₹ 1,10,714.64 | |
| | Tocris Bioscience™ PH 797804 | Fischer Scientific | ₹ 26,480.82 | |
 | 1358027-80-1 | (S)-(-)-PH-797804 | A2B Chem | -- |
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Description
- Potent and selective p38α/β inhibitor (IC50 values are 26 and 102 nM, respectively)
- Exhibits >100-fold selectivity for p38α/β over 71 other kinases, enzymes and GPCRs, including p38γ, p38δ, JNK and ERK2
- Inhibits LPS-induced TNFα production in U937 monocytes in vitro
- Suppresses acute and chronic inflammatory responses in rat models of arthritis
- Orally active
- PH 797804 is the (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: (-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide
Target: p38 Inhibitors
Formula Weight: 477.3
CAS: 1358027-80-1
Molecular Formula: C22H19BrF2N2O3
Purity: >98%
Chemical Name or Material:
(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide
Target:
p38 Inhibitors
Formula Weight:
477.3
CAS:
1358027-80-1
Molecular Formula:
C22H19BrF2N2O3
Purity:
>98%
Chemical Name or Material: 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione
Target: Multidrug Transporter Inhibitors
Formula Weight: 294.42
CAS: 315702-40-0
Molecular Formula: C11H10N4S3
Purity: >98%
Chemical Name or Material:
5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione
Target:
Multidrug Transporter Inhibitors
Formula Weight:
294.42
CAS:
315702-40-0
Molecular Formula:
C11H10N4S3
Purity:
>98%
Chemical Name or Material: 2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide
Target: Nuclear Receptor Agonists
Formula Weight: 397.7
CAS: 303126-97-8
Molecular Formula: C16H10ClF6NO2
Purity: >98%
Chemical Name or Material:
2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide
Target:
Nuclear Receptor Agonists
Formula Weight:
397.7
CAS:
303126-97-8
Molecular Formula:
C16H10ClF6NO2
Purity:
>98%
Chemical Name or Material: 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
Target: Ca2+-ATPase Activators
Formula Weight: 320.38
CAS: 892711-75-0
Molecular Formula: C20H20N2O2
Purity: >98%
Chemical Name or Material:
4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
Target:
Ca2+-ATPase Activators
Formula Weight:
320.38
CAS:
892711-75-0
Molecular Formula:
C20H20N2O2
Purity:
>98%