7110942
Tocris Bioscience™ Adaptaquin
HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
Manufacturer: Fischer Scientific
CAS Number: 385786-48-1
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Chemical Name or Material
7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol
Target
Hydrolase Inhibitors
Formula Weight
377.82
CAS
385786-48-1
Molecular Formula
C21H16ClN3O2
Purity
>97%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Adaptaquin | Fischer Scientific | ₹ 20,048.42 | |
| | Tocris Bioscience™ Adaptaquin | Fischer Scientific | ₹ 83,865.91 | |
 | MilliporeSigma™ Calbiochem™ HIF Prolyl Hydroxylase Inhibitor | MilliporeSigma™ | ₹ 14,736.00 | |
 | 385786-48-1 | Adaptaquin | A2B Chem | ₹ 5,646.96 - ₹ 53,303.88 |
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Description
- HIF-prolyl hydroxylase-2 (PHD2) inhibitor
- Blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD
- Exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes
- Brain penetrant
- Also antioxidant.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol
Target: Hydrolase Inhibitors
Formula Weight: 377.82
CAS: 385786-48-1
Molecular Formula: C21H16ClN3O2
Purity: >97%
Chemical Name or Material:
7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol
Target:
Hydrolase Inhibitors
Formula Weight:
377.82
CAS:
385786-48-1
Molecular Formula:
C21H16ClN3O2
Purity:
>97%
Chemical Name or Material: α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid
Target: Additional Synthetic Protease Inhibitors
Formula Weight: 439.38
CAS: 393105-53-8
Molecular Formula: C24H16F3NO4
Purity: >98%
Chemical Name or Material:
α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid
Target:
Additional Synthetic Protease Inhibitors
Formula Weight:
439.38
CAS:
393105-53-8
Molecular Formula:
C24H16F3NO4
Purity:
>98%
Chemical Name or Material: 4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate
Target: Carbonic Anhydrase Inhibitors
Formula Weight: 335.38
CAS: 1330061-67-0
Molecular Formula: C15H17N3O4S
Purity: >99%
Chemical Name or Material:
4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate
Target:
Carbonic Anhydrase Inhibitors
Formula Weight:
335.38
CAS:
1330061-67-0
Molecular Formula:
C15H17N3O4S
Purity:
>99%
Chemical Name or Material: 3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol
Target: Other Kinase Inhibitors
Formula Weight: 275.3
CAS: 1600515-49-8
Molecular Formula: C17H13N3O
Purity: >98%
Chemical Name or Material:
3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol
Target:
Other Kinase Inhibitors
Formula Weight:
275.3
CAS:
1600515-49-8
Molecular Formula:
C17H13N3O
Purity:
>98%