7146017

Tocris Bioscience™ LM22B 10

TrkB and TrkC agonist; brain penetrant

Manufacturer: Fischer Scientific

CAS Number: 342777-54-2

The price for this product is unavailable. Please request a quote

Chemical Name or Material

2,2′,2′,2′′′-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol

CAS

342777-54-2

Molecular Formula

C27H33ClN2O4

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
60-371-0
Tocris Bioscience™ LM22B 10
Fischer Scientific ₹ 20,277.72
60-375-0
Tocris Bioscience™ LM22B 10
Fischer Scientific ₹ 83,506.56
50-226-1630
Medchemexpress LLC HY-104047 5mg , LM22B-10 CAS:342777-54-2 Purity:>98%
Medchemexpress LLC ₹ 9,882.18
AR003B7Z
2-[[4-[[4-[Bis-(2-hydroxyethyl)-amino]-phenyl]-(4-chloro-phenyl)-methyl]-phenyl]-(2-hydroxy-ethyl)-amino]-ethanol
Aaron Chemicals LLC ₹ 8,556.00 - ₹ 1,30,650.12
AB53411
342777-54-2 | Lm22b-10
A2B Chem ₹ 4,705.80 - ₹ 42,523.32

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Description

  • TrkB and TrkC agonist
  • Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro
  • Exhibits no significant activity in a screen of 57 other receptors and transporters
  • Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively
  • Active in vivo and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

7146017

TrkB and TrkC agonist; brain penetr...


Chemical Name or Material:
2,2′,2′,2′′′-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol

CAS:
342777-54-2

Molecular Formula:
C27H33ClN2O4

Purity:
98%

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Fischer Scientific

7146020

Potent Smo antagonist...


Chemical Name or Material:
1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt

CAS:
2030410-25-2

Molecular Formula:
C21H22N6O.C4H4O4

Purity:
98%

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Fischer Scientific

7146022

K+ channel activator...


Chemical Name or Material:
__

CAS:
85371-64-8

Molecular Formula:
C13H19N5· H2O

Purity:
>98% (HPLC); NMR (conforms)

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Fischer Scientific

7146022

K+ channel activator...


Chemical Name or Material:
__

CAS:
85371-64-8

Molecular Formula:
C13H19N5· H2O

Purity:
>98% (HPLC); NMR (conforms)