7161604
Tocris Bioscience™ PSEM 308 hydrochloride
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
Manufacturer: Fischer Scientific
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Chemical Name or Material
5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride
Molecular Formula
C17H21N3.HCl
Purity
98%
Target
Pharmacologically Selective Effector Molecules/PSEM
Formula Weight
303.83
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Description
- PSAM (pharmacologically selective actuator module) agonist
- Activates PSAML141F-GlyR chimeric ion channels
- Inhibits activity of neurons expressing PSAML141F-GlyR in vivo and activates locus coeruleus noradrenergic neurons expressing PSAML141F,Y115F-5-HT3 ion channels
- Recommended concentration for use in mice is 5 mg/kg or lower
- Plasmid vectors for the transfection of cells with PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 are available from Addgene.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride
Molecular Formula: C17H21N3.HCl
Purity: 98%
Target: Pharmacologically Selective Effector Molecules/PSEM
Formula Weight: 303.83
Chemical Name or Material:
5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride
Molecular Formula:
C17H21N3.HCl
Purity:
98%
Target:
Pharmacologically Selective Effector Molecules/PSEM
Formula Weight:
303.83
Chemical Name or Material: N-[2-(Dimethylamino)ethyl]-12-oxo-12 H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Molecular Formula: C21H20N4O2
Purity: 98%
Target: RNA/DNA Polymerase Inhibitors
Formula Weight: 360.41
Chemical Name or Material:
N-[2-(Dimethylamino)ethyl]-12-oxo-12 H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Molecular Formula:
C21H20N4O2
Purity:
98%
Target:
RNA/DNA Polymerase Inhibitors
Formula Weight:
360.41
Chemical Name or Material: 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid
Molecular Formula: C15H11Cl2NO4
Purity: 98%
Target: __
Formula Weight: 340.16
Chemical Name or Material:
4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid
Molecular Formula:
C15H11Cl2NO4
Purity:
98%
Target:
__
Formula Weight:
340.16
Chemical Name or Material: N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine
Molecular Formula: C19H22ClN5O
Purity: 98%
Target: __
Formula Weight: 371.86
Chemical Name or Material:
N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine
Molecular Formula:
C19H22ClN5O
Purity:
98%
Target:
__
Formula Weight:
371.86