7161690
Tocris Bioscience™ uPSEM 817 tartrate
Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
Manufacturer: Fischer Scientific
CAS Number: 2341833-14-3
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Chemical Name or Material
2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
Target
Pharmacologically Selective Effector Molecules/PSEM
Formula Weight
419.43
CAS
2341833-14-3
Molecular Formula
C16H19N3O.C4H6O6
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ uPSEM 817 tartrate | Fischer Scientific | ₹ 1,06,622.00 | |
| | Tocris Bioscience™ uPSEM 817 tartrate | Fischer Scientific | ₹ 27,812.50 |
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Description
- Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively)
- Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices
- Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
Target: Pharmacologically Selective Effector Molecules/PSEM
Formula Weight: 419.43
CAS: 2341833-14-3
Molecular Formula: C16H19N3O.C4H6O6
Purity: 98%
Chemical Name or Material:
2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
Target:
Pharmacologically Selective Effector Molecules/PSEM
Formula Weight:
419.43
CAS:
2341833-14-3
Molecular Formula:
C16H19N3O.C4H6O6
Purity:
98%
Chemical Name or Material: 7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine
Target: __
Formula Weight: 360.39
CAS: 722456-31-7
Molecular Formula: C18H12N6OS
Purity: 98%
Chemical Name or Material:
7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine
Target:
__
Formula Weight:
360.39
CAS:
722456-31-7
Molecular Formula:
C18H12N6OS
Purity:
98%
Chemical Name or Material: 3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide
Target: __
Formula Weight: 368.41
CAS: 1232410-49-9
Molecular Formula: C18H16N4O3S
Purity: 98%
Chemical Name or Material:
3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide
Target:
__
Formula Weight:
368.41
CAS:
1232410-49-9
Molecular Formula:
C18H16N4O3S
Purity:
98%
Chemical Name or Material: 2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide
Target: __
Formula Weight: 389.38
CAS: 2055397-28-7
Molecular Formula: C18H13F2N3O3S
Purity: 98%
Chemical Name or Material:
2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide
Target:
__
Formula Weight:
389.38
CAS:
2055397-28-7
Molecular Formula:
C18H13F2N3O3S
Purity:
98%