7161693
Tocris Bioscience™ VE 821
High affinity and selective ATP-competitive ATR inhibitor (Ki = 13 nM)
Manufacturer: Fischer Scientific
CAS Number: 1232410-49-9
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Chemical Name or Material
3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide
Molecular Formula
C18H16N4O3S
Purity
98%
CAS
1232410-49-9
Formula Weight
368.41
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ VE 821 | Fischer Scientific | ₹ 39,160.00 | |
| | Tocris Bioscience™ VE 821 | Fischer Scientific | ₹ 10,235.00 | |
 | Apexbio Technology LLC Cell-permeable and ATP-competitive ATM kinase inhibitor 1232410-49-9. MFCD19443686 | Apexbio Technology LLC | ₹ 5,696.00 | |
 | Sigma Aldrich Fine Chemicals Biosciences VE-821 >=98% (HPLC) | 1232410-49-9 | MFCD19443686 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 50,730.00 | |
| | Apexbio Technology LLC VE-821, 10MM (IN 1ML DMSO) Cas No: 1232410-49-9 MFCD: MFCD19443686 | Apexbio Technology LLC | ₹ 7,031.00 | |
 | Sigma Aldrich Fine Chemicals Biosciences VE-821 | 1232410-49-9 | MFCD19443686 | 5 mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 13,192.47 | |
 | Medchemexpress LLC HY-14731 10mg Medchemexpress, VE-821 CAS:1232410-49-9 Purity:>98% | Medchemexpress LLC | ₹ 8,784.30 | |
 | 2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl- | Aaron Chemicals LLC | ₹ 801.00 - ₹ 46,725.00 |
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Description
- Exhibits >75-fold selectivity for ATR over related kinases mTOR, DNA-PK, PI 3-Kγ and PIKKs (Ki values are >1, 2.2, 3.9 and 16 μM, respectively) and a panel of other kinases Induces cell death in colon cancer cell lines in vitro and sensitizes tumor cells to treatment with DNA damaging anticancer agents
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide
Molecular Formula: C18H16N4O3S
Purity: 98%
CAS: 1232410-49-9
Formula Weight: 368.41
Chemical Name or Material:
3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide
Molecular Formula:
C18H16N4O3S
Purity:
98%
CAS:
1232410-49-9
Formula Weight:
368.41
Chemical Name or Material: 2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide
Molecular Formula: C18H13F2N3O3S
Purity: 98%
CAS: 2055397-28-7
Formula Weight: 389.38
Chemical Name or Material:
2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide
Molecular Formula:
C18H13F2N3O3S
Purity:
98%
CAS:
2055397-28-7
Formula Weight:
389.38
Chemical Name or Material: Ethyl 3-[2-(tert-butylamino)-1-[N-(4-chlorobenzyl)formamido]-2-oxoethyl]-6-chloro-1H-indole-2-carboxylate
Molecular Formula: C25H27Cl2N3O4
Purity: 98%
CAS: 1364488-67-4
Formula Weight: 504.41
Chemical Name or Material:
Ethyl 3-[2-(tert-butylamino)-1-[N-(4-chlorobenzyl)formamido]-2-oxoethyl]-6-chloro-1H-indole-2-carboxylate
Molecular Formula:
C25H27Cl2N3O4
Purity:
98%
CAS:
1364488-67-4
Formula Weight:
504.41
Chemical Name or Material: 4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide
Molecular Formula: C19H27ClFN3O2
Purity: 98%
CAS: 1199236-64-0
Formula Weight: 383.89
Chemical Name or Material:
4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide
Molecular Formula:
C19H27ClFN3O2
Purity:
98%
CAS:
1199236-64-0
Formula Weight:
383.89