7166781
Tocris™ A 410099.1
High affinity XIAP antagonist
Manufacturer: Fischer Scientific
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Molecular Formula
C27H40N4O3.HCl
Formula Weight
505.09
Product Type
Antagonist
Purity
98%
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Description
- High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP)
- Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells)
- Also displays antitumor activity in a mouse breast cancer xenograft model
- Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Molecular Formula: C27H40N4O3.HCl
Formula Weight: 505.09
Product Type: Antagonist
Purity: 98%
Molecular Formula:
C27H40N4O3.HCl
Formula Weight:
505.09
Product Type:
Antagonist
Purity:
98%
Molecular Formula: C33H25NO8Na2
Formula Weight: 609.54
Product Type: Antagonist
Purity: 98%
Molecular Formula:
C33H25NO8Na2
Formula Weight:
609.54
Product Type:
Antagonist
Purity:
98%
Molecular Formula: C18H16FN3O
Formula Weight: 309.34
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C18H16FN3O
Formula Weight:
309.34
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C22H21ClN4O4
Formula Weight: 440.88
Product Type: Agonist
Purity: 98%
Molecular Formula:
C22H21ClN4O4
Formula Weight:
440.88
Product Type:
Agonist
Purity:
98%