7166796

Tocris™ TAK 375

Very high affinity and selective melatonin receptor agonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Synonym

Ramelteon

Formula Weight

259.34

Purity

98%

Molecular Formula

C16H21NO2

Product Type

Agonist

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Description

  • Very high affinity and selective melatonin agonist (Ki values are 14 and 112 pM for human MT1 and MT2, respectively)
  • Selective for human MT1 and MT2 over hamster MT3 and a range of other targets including benzodiazepine, opiate and dopamine receptors, ion channels and transporters
  • Accelerates return to normal circadian rhythm in rats after phase shift, without affecting learning and memory
  • Also reduces infarct size in rat heart in vitro post ischemia-reperfusion.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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