7166822
Tocris™ AMG 333
Potent and selective TRPM8 antagonist
Manufacturer: Fischer Scientific
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Molecular Formula
C20H12F5N3O4
Formula Weight
453.33
Product Type
Antagonist
Purity
98%
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Description
- AMG 333 is a potent and selective TRPM8 antagonist (IC50 values are 13 and 20 nM for hTRPM8 and rTRPM8, respectively)
- Displays high selectivity over other TRP channels (IC50 >20 μM, TRPV1/V3/V4/A1)
- Inhibits icilin-induced wet-dog shake in rats and suppresses cold-induced increases in blood pressure in the rat cold-pressor test.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Molecular Formula: C20H12F5N3O4
Formula Weight: 453.33
Product Type: Antagonist
Purity: 98%
Molecular Formula:
C20H12F5N3O4
Formula Weight:
453.33
Product Type:
Antagonist
Purity:
98%
Molecular Formula: C20H31BrN2O2
Formula Weight: 411.38
Product Type: Blocker
Purity: 98%
Molecular Formula:
C20H31BrN2O2
Formula Weight:
411.38
Product Type:
Blocker
Purity:
98%
Molecular Formula: C19H21N3O2
Formula Weight: 323.4
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C19H21N3O2
Formula Weight:
323.4
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C18H17Cl2N5
Formula Weight: 374.27
Product Type: Channel Activator
Purity: 98%
Molecular Formula:
C18H17Cl2N5
Formula Weight:
374.27
Product Type:
Channel Activator
Purity:
98%