72-825
Tocris™ Bortezomib
Manufacturer: Fischer Scientific
CAS Number: 179324-69-7
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-825-Each-of-1 | In Stock | ₹ 11,627.60 |
72-825 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,627.60
GST (18%): ₹ 2,092.968
Total Price: ₹ 13,720.568
Chemical Name or Material
B-[(1 R)-3-Methyl-1-[[(2 S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
Quantity
5 mg
Molecular Formula
C19H25BN4O4
CAS
179324-69-7
Target
Proteasome Inhibitors
Purity
0.98
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Description
- Bortezomib is a high affinity proteasome inhibitor (Ki = 0.6 nM)
- Inhibits growth of multiple myeloma (MM) cell lines (IC50 values in <50 nM range); induces apoptosis in MM cell lines and MM patient derived cells, including p53 mutant cell lines
- Decreases adherence of MM cells lines to bone marrow stromal cells (BMSCs)
- Acts synergistically with dexamethasone (Cat
- No
- 1126)
- Also cytotoxic in MCF-7 breast cancer cell line (IC50 = 50 nM).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: B-[(1 R)-3-Methyl-1-[[(2 S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
Quantity: 5 mg
Molecular Formula: C19H25BN4O4
CAS: 179324-69-7
Target: Proteasome Inhibitors
Purity: 0.98
Chemical Name or Material:
B-[(1 R)-3-Methyl-1-[[(2 S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
Quantity:
5 mg
Molecular Formula:
C19H25BN4O4
CAS:
179324-69-7
Target:
Proteasome Inhibitors
Purity:
0.98
Chemical Name or Material: 5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5-(2,2,2-trifluoroethyl)-6 H-pyrimido[4,5-b][1,4 ]benzodiazepin-6-one
Quantity: 5 mg
Molecular Formula: C26H28F3N7O2
CAS: 2222635-15-4
Target: Other Kinase Inhibitors
Purity: 0.98
Chemical Name or Material:
5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5-(2,2,2-trifluoroethyl)-6 H-pyrimido[4,5-b][1,4 ]benzodiazepin-6-one
Quantity:
5 mg
Molecular Formula:
C26H28F3N7O2
CAS:
2222635-15-4
Target:
Other Kinase Inhibitors
Purity:
0.98
Chemical Name or Material: __
Quantity: 1 mg
Molecular Formula: C71H84N10O25
CAS: __
Target: Other Fluorescent Probes
Purity: 0.95
Chemical Name or Material:
__
Quantity:
1 mg
Molecular Formula:
C71H84N10O25
CAS:
__
Target:
Other Fluorescent Probes
Purity:
0.95
Chemical Name or Material: (2 aR,5 aR,6 S,6 aR,8 R,9 aR,10 AS,10 bR,10 cR)-8-(3-Furanyl)-2 A,5 A,6,6 A,8,9,9 A,10 A,10 b,10 c-decahydro-2 A,5 A,6 A,7-tetramethyl-2,5-dioxo-2 H,5 H-cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid methyl ester
Quantity: 25 mg
Molecular Formula: C27H30O7
CAS: 25990-37-8
Target: Ubiquitin Ligase (E3) Inhibitors
Purity: 0.97
Chemical Name or Material:
(2 aR,5 aR,6 S,6 aR,8 R,9 aR,10 AS,10 bR,10 cR)-8-(3-Furanyl)-2 A,5 A,6,6 A,8,9,9 A,10 A,10 b,10 c-decahydro-2 A,5 A,6 A,7-tetramethyl-2,5-dioxo-2 H,5 H-cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid methyl ester
Quantity:
25 mg
Molecular Formula:
C27H30O7
CAS:
25990-37-8
Target:
Ubiquitin Ligase (E3) Inhibitors
Purity:
0.97