7222995
Tocris Bioscience™ CB 5083
Potent p97 ATPase inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1542705-92-9
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Chemical Name or Material
1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Target
p97 ATPase Inhibitors
Purity
0.98
CAS
1542705-92-9
Molecular Formula
C24H23N5O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ CB 5083 | Fischer Scientific | ₹ 64,881.00 | |
| | Tocris Bioscience™ CB 5083 | Fischer Scientific | ₹ 15,432.60 | |
 | Medchemexpress LLC HY-12861 100mg , CB-5083 CAS:1542705-92-9 Purity:>98% | Medchemexpress LLC | ₹ 91,581.00 | |
 | Selleck Chemical LLC CB-5083 5mg 1542705-92-9 | Selleck Chemical LLC | ₹ 18,903.60 | |
 | Apexbio Technology LLC CB-5083, 1542705-92-9, MFCD28963914, 5 mg | Apexbio Technology LLC | ₹ 5,785.00 | |
 | eMolecules Ambeed / 1-(4-(Benzylamino)-78-dihydro-5H-pyrano[43-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide / 10mg / 534567759 / A287921 / / 1542705-92-9 / MFCD28963914 / 413.481 / C24H23N5O2 | eMolecules | ₹ 10,087.26 | |
 | Medchemexpress LLC HY-12861 10mg Medchemexpress, CB-5083 CAS:1542705-92-9 Purity:>98% | Medchemexpress LLC | ₹ 15,886.50 | |
| | Apexbio Technology LLC CB-5083, 1542705-92-9, MFCD28963914, 10 mg | Apexbio Technology LLC | ₹ 10,769.00 |
Related Products
Description
- CB 5083 is a potent p97 inhibitor, inhibiting the D2 ATPase domain (IC50 = 11 nM)
- CB 5083 shows broad antitumor activity and inhibits tumor growth in vivo
- CB 5083 is cytotoxic to A549 cancer cells (IC50 = 680 nM), increases CHOP and GRP78 protein levels and results in the loss of aggresomes.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Target: p97 ATPase Inhibitors
Purity: 0.98
CAS: 1542705-92-9
Molecular Formula: C24H23N5O2
Chemical Name or Material:
1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Target:
p97 ATPase Inhibitors
Purity:
0.98
CAS:
1542705-92-9
Molecular Formula:
C24H23N5O2
Chemical Name or Material: (2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one
Target: Orphan 7-TM Receptor Antagonists
Purity: 0.98
CAS: 1239987-91-7
Molecular Formula: C15H14OS
Chemical Name or Material:
(2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one
Target:
Orphan 7-TM Receptor Antagonists
Purity:
0.98
CAS:
1239987-91-7
Molecular Formula:
C15H14OS
Chemical Name or Material: N-[5-[[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide
Target: Casein Kinase 2 Inhibitors
Purity: 0.98
CAS: 2470424-39-4
Molecular Formula: C20H21N7O
Chemical Name or Material:
N-[5-[[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide
Target:
Casein Kinase 2 Inhibitors
Purity:
0.98
CAS:
2470424-39-4
Molecular Formula:
C20H21N7O
Chemical Name or Material: 1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains
Target: Bromodomain Inhibitors
Purity: 0.98
CAS: 1997319-84-2
Molecular Formula: C19H25N5O3
Chemical Name or Material:
1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains
Target:
Bromodomain Inhibitors
Purity:
0.98
CAS:
1997319-84-2
Molecular Formula:
C19H25N5O3