7222996

Tocris Bioscience™ GPR52 Comp-43

GPR52 receptor antagonist

Manufacturer: Fischer Scientific

CAS Number: 1239987-91-7

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Chemical Name or Material

(2 E)-5-Phenyl-1-(2-thienyl)-2-penten-1-one

Target

Orphan 7-TM Receptor Antagonists

Purity

0.98

CAS

1239987-91-7

Molecular Formula

C15H14OS

Other Options

Image Product Name Manufacturer Price Range
74-451-0
Tocris Bioscience™ GPR52 Comp-43
Fischer Scientific ₹ 12,009.20
74-455-0
Tocris Bioscience™ GPR52 Comp-43
Fischer Scientific ₹ 50,617.30
50-244-7443
eMolecules​ Medchem Express / GPR52 antagonist-1 / 5mg / 716993791 / HY-145468 / / 1239987-91-7 / [null] / 242.340 / C15H14OS
eMolecules​ ₹ 8,816.10

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Description

  • Description GPR52 Comp-43 is a GPR52 receptor antagonist (IC50 = 0.63 μM)
  • The use of GPR52 Comp-43 in animal models of Huntington's Disease leads to degradation and reduction of soluble and aggregated mutant huntingtin protein in the striatum
  • It also reduces neuronal loss, promotes neuronal survival and improves motor functions in vivo
  • GPR52 Comp-43 is active in vitro and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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