7223000
Tocris Bioscience™ SGC SMARCA-BRDVIII
Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1997319-84-2
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Chemical Name or Material
1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains
Target
Bromodomain Inhibitors
Purity
0.98
CAS
1997319-84-2
Molecular Formula
C19H25N5O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ SGC SMARCA-BRDVIII | Fischer Scientific | ₹ 15,780.69 | |
| | Tocris Bioscience™ SGC SMARCA-BRDVIII | Fischer Scientific | ₹ 67,191.98 | |
 | Medchemexpress LLC HY-145446 100mg , SGC-SMARCA-BRDVIII CAS:1997319-84-2 Purity:>98% | Medchemexpress LLC | ₹ 68,995.58 | |
 | tert-Butyl 4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazine-1-carboxylate | Aaron Chemicals LLC | ₹ 6,588.12 - ₹ 1,01,131.92 |
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Description
- Description SGC-SMARCA-BRDVIII is a selective and high affinity SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomains (Kd(ITC) values are 35, 36 and 13 nM, respectively)
- SGC-SMARCA-BRDVIII exhibits selectivity over 25 other bromodomain families and shows no off-target activity on 85 protein kinases screened using temperature-shift binding assays
- SGC-SMARCA-BRDVIII suppresses formation of 3T3-L1 mouse fibroblasts into adipocytes (EC50 <1.0 μM).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains
Target: Bromodomain Inhibitors
Purity: 0.98
CAS: 1997319-84-2
Molecular Formula: C19H25N5O3
Chemical Name or Material:
1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains
Target:
Bromodomain Inhibitors
Purity:
0.98
CAS:
1997319-84-2
Molecular Formula:
C19H25N5O3
Chemical Name or Material: Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Target: Proteasome Modulators
Purity: 0.98
CAS: 1446350-60-2
Molecular Formula: C39H37N3O3
Chemical Name or Material:
Ethyl (4 R,5 R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1 H-imidazole-4-carboxylate
Target:
Proteasome Modulators
Purity:
0.98
CAS:
1446350-60-2
Molecular Formula:
C39H37N3O3
Chemical Name or Material: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
Target: VEGF Receptor Inhibitors
Purity: 0.98
CAS: 443913-73-3
Molecular Formula: C22H24BrFN4O2
Chemical Name or Material:
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
Target:
VEGF Receptor Inhibitors
Purity:
0.98
CAS:
443913-73-3
Molecular Formula:
C22H24BrFN4O2
Chemical Name or Material: 6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide
Target: Molecular Glues
Purity: 0.98
CAS: 790245-61-3
Molecular Formula: C17H16N2O2S
Chemical Name or Material:
6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide
Target:
Molecular Glues
Purity:
0.98
CAS:
790245-61-3
Molecular Formula:
C17H16N2O2S