7249498
Tocris Bioscience™ Sonidegib
Potent Smoothened receptor antagonist
Manufacturer: Fischer Scientific
CAS Number: 956697-53-3
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CAS
956697-53-3
Target
Smoothened
Molecular Formula
C26H26F3N3O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Sonidegib | Fischer Scientific | ₹ 97,795.08 | |
| | Tocris Bioscience™ Sonidegib | Fischer Scientific | -- | |
| | Enzo Life Sciences Sonidegib (free base) (25mg). CAS: 956697-53-3 | Enzo Life Sciences | ₹ 31,879.66 | |
| | Enzo Life Sciences Sonidegib (free base) (500mg). CAS: 956697-53-3 | Enzo Life Sciences | ₹ 2,67,660.77 | |
| | Enzo Life Sciences Sonidegib (free base) (100mg). CAS: 956697-53-3 | Enzo Life Sciences | ₹ 87,202.75 | |
| | Enzo Life Sciences Sonidegib (free base) (50mg). CAS: 956697-53-3 | Enzo Life Sciences | ₹ 52,305.39 | |
 | Selleck Chemical LLC Sonidegib (NVP-LDE225) 25mg 956697-53-3 Erismodegib | Selleck Chemical LLC | ₹ 47,451.58 | |
 | eMolecules Erismodegib | 956697-53-3 | | 50mg | eMolecules | ₹ 25,354.85 | |
| | Medchemexpress LLC HY-16582A 10mg Medchemexpress, Sonidegib CAS:956697-53-3 Purity:>98% | Medchemexpress LLC | ₹ 8,265.10 | |
| | Enzo Life Sciences Sonidegib (free base) (10mg). CAS: 956697-53-3 | Enzo Life Sciences | ₹ 17,710.92 |
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Description
- Sonidegib is a potent Smoothened (Smo) receptor antagonist (IC50 values are 1.3 nM and 2.5 nM at mouse and human receptors, respectively)
- Inhibits growth of a variety of tumor types including basal cell carcinoma, small cell lung cancer and medulloblastoma
- Sonidegib inhibits Hh pathway in CD34+ chronic myeloid leukemia cells; it reduces both the number of cells and self-renewal ability
- Brain penetrant and orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
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CAS: 956697-53-3
Target: Smoothened
Molecular Formula: C26H26F3N3O3
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956697-53-3
Target:
Smoothened
Molecular Formula:
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