78-261-0

Tocris Bioscience™ Sonidegib

Manufacturer: Fischer Scientific

CAS Number: 956697-53-3

The price for this product is unavailable. Please request a quote

Chemical Name or Material

rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide

Quantity

10 mg

Molecular Formula

C26H26F3N3O3

CAS

956697-53-3

Target

Smoothened

Other Options

Image Product Name Manufacturer Price Range
7249498
Tocris Bioscience™ Sonidegib
Fischer Scientific --
78-265-0
Tocris Bioscience™ Sonidegib
Fischer Scientific ₹ 97,795.08
50-201-3665
Enzo Life Sciences Sonidegib (free base) (25mg). CAS: 956697-53-3
Enzo Life Sciences ₹ 31,879.66
50-201-3669
Enzo Life Sciences Sonidegib (free base) (500mg). CAS: 956697-53-3
Enzo Life Sciences ₹ 2,67,660.77
50-201-3667
Enzo Life Sciences Sonidegib (free base) (100mg). CAS: 956697-53-3
Enzo Life Sciences ₹ 87,202.75
50-201-3666
Enzo Life Sciences Sonidegib (free base) (50mg). CAS: 956697-53-3
Enzo Life Sciences ₹ 52,305.39
50-644-0
Selleck Chemical LLC Sonidegib (NVP-LDE225) 25mg 956697-53-3 Erismodegib
Selleck Chemical LLC ₹ 47,451.58
50-215-4998
eMolecules​ Erismodegib | 956697-53-3 | | 50mg
eMolecules​ ₹ 25,354.85
50-202-9205
Medchemexpress LLC HY-16582A 10mg Medchemexpress, Sonidegib CAS:956697-53-3 Purity:>98%
Medchemexpress LLC ₹ 8,265.10
50-201-3664
Enzo Life Sciences Sonidegib (free base) (10mg). CAS: 956697-53-3
Enzo Life Sciences ₹ 17,710.92

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Description

  • Sonidegib is a potent Smoothened (Smo) receptor antagonist (IC50 values are 1.3 nM and 2.5 nM at mouse and human receptors, respectively)
  • Inhibits growth of a variety of tumor types including basal cell carcinoma, small cell lung cancer and medulloblastoma
  • Sonidegib inhibits Hh pathway in CD34+ chronic myeloid leukemia cells; it reduces both the number of cells and self-renewal ability
  • Brain penetrant and orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Chemical Name or Material:
rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide

Quantity:
10 mg

Molecular Formula:
C26H26F3N3O3

CAS:
956697-53-3

Target:
Smoothened

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Chemical Name or Material:
rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide

Quantity:
50 mg

Molecular Formula:
C26H26F3N3O3

CAS:
956697-53-3

Target:
Smoothened

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