7180145

Tocris™ A 1899

Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker

Manufacturer: Fischer Scientific

CAS Number: 498577-46-1

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Chemical Name or Material

N-[(2,4-Difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl][1,1'-biphenyl]-2-carboxamide

CAS

498577-46-1

Molecular Formula

C30H26F2N2O3

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
69-725
Tocris™ A 1899
Fischer Scientific ₹ 11,328.14
69-722-5
Tocris™ A 1899
Fischer Scientific ₹ 44,020.62

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Description

  • Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) channel blocker (IC50 values are 7 nM and 70 nM for human TASK-1 and TASK-3 expressed in CHO cells, respectively)
  • Displays >12.5-fold selectivity for TASK-1 and TASK-3 over other K+ channels (IC50 = 0.9 μM for K2P18.1/TRESK and >2 μM for all other channels tested)
  • Binds within open channel pore.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
N-[(2,4-Difluorophenyl)methyl]-2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl][1,1'-biphenyl]-2-carboxamide

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