7250140
Tocris Bioscience™ RIPA 56
Potent and metabolically stable RIP1 kinase inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1956370-21-0
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Chemical Name or Material
N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide
Target
RIP Kinase Inhibitors
Purity
0.98
CAS
1956370-21-0
Molecular Formula
C13H19NO2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ RIPA 56 | Fischer Scientific | ₹ 10,926.01 | |
| | Tocris Bioscience™ RIPA 56 | Fischer Scientific | ₹ 45,517.92 | |
 | Medchemexpress LLC HY-101032 10mg Medchemexpress, RIPA-56 CAS:1956370-21-0 Purity:>98% | Medchemexpress LLC | ₹ 5,929.31 | |
 | Sigma Aldrich Fine Chemicals Biosciences RIPA-56 >=98% (HPLC) | 1956370-21-0 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 7,246.93 | |
 | Sigma Aldrich Fine Chemicals Biosciences RIPA-56 >=98% (HPLC) | 1956370-21-0 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 21,381.44 | |
 | 1956370-21-0 | RIPA-56 | A2B Chem | ₹ 7,443.72 - ₹ 68,191.32 |
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Description
- RIPA 56 is a potent and metabolically stable receptor-interacting protein kinase 1 (RIPK1) inhibitor (EC50 = 13 nM)
- RIPA-56 shows no inhibition of RIP3 kinase at 10 μM
- RIPA 56 blocks necroptosis and aging of the mouse male reproductive system
- RIPA 56 reduces tumor necrosis factor α (TNFα)-induced mortality and multi-organ damage in a mouse model of systemic inflammatory response syndrome (SIRS)
- RIPA 56 is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide
Target: RIP Kinase Inhibitors
Purity: 0.98
CAS: 1956370-21-0
Molecular Formula: C13H19NO2
Chemical Name or Material:
N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide
Target:
RIP Kinase Inhibitors
Purity:
0.98
CAS:
1956370-21-0
Molecular Formula:
C13H19NO2
Chemical Name or Material: N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride
Target: Additional Nuclear Receptor Compounds
Purity: 0.98
CAS: 1049691-47-5
Molecular Formula: C17H19N3O2S.HCl
Chemical Name or Material:
N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride
Target:
Additional Nuclear Receptor Compounds
Purity:
0.98
CAS:
1049691-47-5
Molecular Formula:
C17H19N3O2S.HCl
Chemical Name or Material: 2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone
Target: SMPD2
Purity: 0.98
CAS: 14513-15-6
Molecular Formula: C21H16N2O2S
Chemical Name or Material:
2,3-Dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1 H)-pyrimidinone
Target:
SMPD2
Purity:
0.98
CAS:
14513-15-6
Molecular Formula:
C21H16N2O2S
Chemical Name or Material: 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1 R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Target: Bcl-2 Family Inhibitors
Purity: 0.98
CAS: 923564-51-6
Molecular Formula: C47H55ClF3N5O6S3
Chemical Name or Material:
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1 R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Target:
Bcl-2 Family Inhibitors
Purity:
0.98
CAS:
923564-51-6
Molecular Formula:
C47H55ClF3N5O6S3