7250147

Tocris Bioscience™ RECTAS

IKBKAP pre-mRNA splicing modulator

Manufacturer: Fischer Scientific

CAS Number: 101862-47-9

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Chemical Name or Material

2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine

Target

DNA, RNA and Protein Synthesis Compounds

Purity

0.98

CAS

101862-47-9

Molecular Formula

C10H8ClN5O

Other Options

Image Product Name Manufacturer Price Range
76-791-0
Tocris Bioscience™ RECTAS
Fischer Scientific ₹ 18,181.50
76-795-0
Tocris Bioscience™ RECTAS
Fischer Scientific ₹ 76,276.74
50-244-1015
eMolecules​ ChemScene / 2-Chloro-N6-furfuryladenine / 250mg / 626491842 / CS-0100010 / 0.000 / 101862-47-9 / [null] / 249.660 / C10H8ClN5O
eMolecules​ ₹ 3,292.35
CS-0100010
2-Chloro-N6-furfuryladenine
ChemScene ₹ 1,283.40 - ₹ 48,598.08
AE23182
101862-47-9 | (2-CHLORO-7H-PURIN-6-YL)-FURAN-2-YLMETHYL-AMINE
A2B Chem ₹ 1,283.40 - ₹ 4,876.92

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Description

  • RECTAS (rectifier of aberrant splicing) is a pre-mRNA splicing modulator of the IKBKAP (inhibitor of κ light polypeptide gene enhancer in B-cells, kinase complex associated protein) gene
  • It corrects aberrant IKBKAP splicing in vitro in cellular models of familial dysautonomia and in vivo in transgenic mice
  • In combination with Phenylbutyric acid (Cat
  • No
  • 2682), RECTAS rescues PARK7 aberrant splicing and neuronal cell loss in a midbrain organoid model of familial Parkinson's disease
  • Orally bioavailable and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

7250147

IKBKAP pre-mRNA splicing modulator...


Chemical Name or Material:
2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine

Target:
DNA, RNA and Protein Synthesis Compounds

Purity:
0.98

CAS:
101862-47-9

Molecular Formula:
C10H8ClN5O

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Fischer Scientific

7250150

Potent LMTK3 inhibitor...


Chemical Name or Material:
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine

Target:
LMTK3

Purity:
0.98

CAS:
__

Molecular Formula:
C18H11F3N4O

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Fischer Scientific

7250151

Potent and selective O-GlcNAcase (O...


Chemical Name or Material:
N-[(1-Methyl-1 H-imidazol-4-yl)methyl]-4-(4-methyl-1-piperidinyl)-2-pyrimidinamine

Target:
Hydrolase Inhibitors

Purity:
0.98

CAS:
2757254-99-0

Molecular Formula:
C15H22N6

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7250154

Pan-polymorph STING agonist...


Chemical Name or Material:
1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1 H-indole-6-carboxamide

Target:
STING Agonists

Purity:
0.98

CAS:
2259624-71-8

Molecular Formula:
C25H19ClF4N2O2