75-115-0
Tocris Bioscience™ ARN 3236
Manufacturer: Fischer Scientific
CAS Number: 1613710-01-2
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 75-115-0-Each-of-1 | In Stock | ₹ 44,571.63 |
75-115-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,571.63
GST (18%): ₹ 8,022.893
Total Price: ₹ 52,594.523
Chemical Name or Material
3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1 H-pyrrolo[2,3-b]pyridine
Quantity
50 mg
Molecular Formula
C19H16N2O2S
CAS
1613710-01-2
Target
SNF1LK2/SIK2
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ ARN 3236 | Fischer Scientific | -- | |
| | Tocris Bioscience™ ARN 3236 | Fischer Scientific | ₹ 10,599.17 | |
 | 1613710-01-2 | 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1H-pyrrolo[2,3-b]pyridine | A2B Chem | ₹ 1,540.08 - ₹ 1,54,435.80 |
Related Products
Description
- ARN 3236 is a potent of salt-inducible kinase 2 (SIK2) inhibitor (IC50 values are <1 nM, 6.63 nM and 21.63 nM for SIK2, SIK3 and SIK1 respectively)
- ARN 3236 inhibits centrosome separation by uncoupling the centrosome from the nucleus
- It also induces cell-cycle arrest and apoptosis by attenuating the AKT/survivin pathway
- ARN 3236 inhibits growth and enhances Taxol (Cat
- No
- 1097) sensitivity in ovarian cancer cell lines in vitro and in vivo
- In human myeloid cells, ARN 3236 blocks TNF and induces IL-10 upon LPS stimulation; it also reduces the production of IL-1β upon activation of TLR4 and TLR2 signaling
- In depression models, ARN 3236 exhibits antidepressant-like effects via the hippocampal CRTC1-CREB-BDNF pathway
- ARN 3236 penetrates the blood-brain barrier, and it is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1 H-pyrrolo[2,3-b]pyridine
Quantity: 50 mg
Molecular Formula: C19H16N2O2S
CAS: 1613710-01-2
Target: SNF1LK2/SIK2
Purity: 0.98
Chemical Name or Material:
3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1 H-pyrrolo[2,3-b]pyridine
Quantity:
50 mg
Molecular Formula:
C19H16N2O2S
CAS:
1613710-01-2
Target:
SNF1LK2/SIK2
Purity:
0.98
Chemical Name or Material: 3-Bromo-2-oxopropanoic acid
Quantity: 100 mg
Molecular Formula: C3H3BrO3
CAS: 1113-59-3
Target: Monocarboxylate Transporter Inhibitors
Purity: __
Chemical Name or Material:
3-Bromo-2-oxopropanoic acid
Quantity:
100 mg
Molecular Formula:
C3H3BrO3
CAS:
1113-59-3
Target:
Monocarboxylate Transporter Inhibitors
Purity:
__
Chemical Name or Material: 3-[4-[[2-(2-Azidoethoxy)ethyl]amino]-1,3-dihydro-1-oxo-2 H-isoindol-2-yl]-2,6-piperidinedione
Quantity: 25 mg
Molecular Formula: C17H20N6O4
CAS: 2399455-45-7
Target: Degrader Building Blocks
Purity: 0.95
Chemical Name or Material:
3-[4-[[2-(2-Azidoethoxy)ethyl]amino]-1,3-dihydro-1-oxo-2 H-isoindol-2-yl]-2,6-piperidinedione
Quantity:
25 mg
Molecular Formula:
C17H20N6O4
CAS:
2399455-45-7
Target:
Degrader Building Blocks
Purity:
0.95
Chemical Name or Material: 3-[4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-1,3-dihydro-1-oxo-2 H-isoindol-2-yl]-2,6-piperidinedione
Quantity: 25 mg
Molecular Formula: C19H24N6O5
CAS: 2399455-48-0
Target: Degrader Building Blocks
Purity: 0.95
Chemical Name or Material:
3-[4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-1,3-dihydro-1-oxo-2 H-isoindol-2-yl]-2,6-piperidinedione
Quantity:
25 mg
Molecular Formula:
C19H24N6O5
CAS:
2399455-48-0
Target:
Degrader Building Blocks
Purity:
0.95