75-461-0
Tocris Bioscience™ C28
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 75-461-0-Each-of-1 | In Stock | ₹ 23,273.50 |
75-461-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,273.50
GST (18%): ₹ 4,189.23
Total Price: ₹ 27,462.73
Chemical Name or Material
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target
LMTK3
Purity
0.98
Quantity
10 mg
Molecular Formula
C18H11F3N4O
Related Products
Description
- C28 is a potent lemur tyrosine kinase 3 (LMTK3) inhibitor (IC50 = 67 nM)
- Disrupts interaction of LMTK3 and HSP90 leading to degradation of LMTK3
- Also inhibits CLK, DYRK1α, IRAK4 and HIPK2 (IC50 values are 5 nM, 6 nM, 41 nM and 48 nM respectively)
- C28 inhibits growth and increases apoptosis in breast cancer cell lines (IC50 = 6.5-14.77 μM) and reduces growth of tumors in xenograft and transgenic mouse models of breast cancer
- Also reduces levels of ERα.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target: LMTK3
Purity: 0.98
Quantity: 10 mg
Molecular Formula: C18H11F3N4O
Chemical Name or Material:
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target:
LMTK3
Purity:
0.98
Quantity:
10 mg
Molecular Formula:
C18H11F3N4O
Chemical Name or Material: 6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target: LMTK3
Purity: 0.98
Quantity: 50 mg
Molecular Formula: C18H11F3N4O
Chemical Name or Material:
6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine
Target:
LMTK3
Purity:
0.98
Quantity:
50 mg
Molecular Formula:
C18H11F3N4O
Chemical Name or Material: 2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1 H-indazol-1-yl]methyl]phenoxy]ethanol
Target: Checkpoint Control Kinase Inhibitors
Purity: 0.98
Quantity: 10 mg
Molecular Formula: C27H24F2N6O4
Chemical Name or Material:
2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1 H-indazol-1-yl]methyl]phenoxy]ethanol
Target:
Checkpoint Control Kinase Inhibitors
Purity:
0.98
Quantity:
10 mg
Molecular Formula:
C27H24F2N6O4
Chemical Name or Material: __
Target: __
Purity: __
Quantity: 100 μg
Molecular Formula: __
Chemical Name or Material:
__
Target:
__
Purity:
__
Quantity:
100 μg
Molecular Formula:
__