73-751-0
Tocris Bioscience™ RO 8191
Manufacturer: Tocris Bioscience™
CAS Number: 691868-88-9
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Chemical Name or Material
8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8 ]naphthyridine
Quantity
10 mg
Molecular Formula
C14H5F6N5O
CAS
691868-88-9
Target
IFN-alpha/beta R2
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / RO8191 / 5mg / 572597148 / HY-W063968 / / 691868-88-9 / MFCD03102493 / 373.218 / C14H5F6N5O | eMolecules | ₹ 13,853.88 | |
 | 8-(1,3,4-OXADIAZOL-2-YL)-2,4-BIS(TRIFLUOROMETHYL)IMIDAZO[1,2-A][1,8]NAPHTHYRIDINE | Aaron Chemicals LLC | ₹ 4,021.32 - ₹ 6,844.80 | |
 | 691868-88-9 | 8-(1,3,4-OXADIAZOL-2-YL)-2,4-BIS(TRIFLUOROMETHYL)IMIDAZO[1,2-A][1,8]NAPHTHYRIDINE | A2B Chem | ₹ 2,481.24 - ₹ 89,581.32 |
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Description
- RO 8191 is an IFNα receptor 2 (IFNAR2) agonist (EC50 = 0.2 μM)
- RO 8191 induces phosphorylation and activation of STAT1 and STAT2
- RO 8191 inhibits hepatitis C (HCV) cell culture-produced infectious particles and HCV subgenomic replicon (IC50 values 0.20 μM and 0.17 μM, respectively) and inhibits hepatitis B virus replication in cell cultures (IC50 = 0.1 μM)
- In an animal model RO 8191 inhibits prion invasion and prolongs survival; it also reverses the inhibitory effect of integrin β6 (ITGB6) on the JAK/STAT3 signaling and the epithelial-to-mesenchymal transition pathway and inhibits the proliferation, invasion, and migration of cervical cancer cells
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: 8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8 ]naphthyridine
Quantity: 10 mg
Molecular Formula: C14H5F6N5O
CAS: 691868-88-9
Target: IFN-alpha/beta R2
Purity: 0.98
Chemical Name or Material:
8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8 ]naphthyridine
Quantity:
10 mg
Molecular Formula:
C14H5F6N5O
CAS:
691868-88-9
Target:
IFN-alpha/beta R2
Purity:
0.98
Chemical Name or Material: (2-Aminopyridin-3-yl)(1 H-imidazol-1-yl)methanone
Quantity: 10 mg
Molecular Formula: C9H8N4O
CAS: __
Target: DNA, RNA and Protein Synthesis Compounds
Purity: __
Chemical Name or Material:
(2-Aminopyridin-3-yl)(1 H-imidazol-1-yl)methanone
Quantity:
10 mg
Molecular Formula:
C9H8N4O
CAS:
__
Target:
DNA, RNA and Protein Synthesis Compounds
Purity:
__
Chemical Name or Material: N-[(1 S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5 H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide hydrochloride
Quantity: 10 mg
Molecular Formula: C49H57N11O6.HCl
CAS: 2624332-04-1
Target: NPY Receptor Antagonists
Purity: 0.98
Chemical Name or Material:
N-[(1 S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5 H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide hydrochloride
Quantity:
10 mg
Molecular Formula:
C49H57N11O6.HCl
CAS:
2624332-04-1
Target:
NPY Receptor Antagonists
Purity:
0.98
Chemical Name or Material: 1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Quantity: 25 mg
Molecular Formula: C24H23N5O2
CAS: 1542705-92-9
Target: p97 ATPase Inhibitors
Purity: 0.98
Chemical Name or Material:
1-[7,8-Dihydro-4-[(phenylmethyl)amino]-5 H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1 H-indole-4-carboxamide
Quantity:
25 mg
Molecular Formula:
C24H23N5O2
CAS:
1542705-92-9
Target:
p97 ATPase Inhibitors
Purity:
0.98