78-501-0

Tocris Bioscience™ MK 2206 dihydrochloride

Manufacturer: Fischer Scientific

CAS Number: 1032350-13-2

Select a Size

Pack Size SKU Availability Price
Each of 1 78-501-0-Each-of-1 In Stock ₹ 11,901.40

78-501-0 - Each of 1

₹ 11,901.40

In Stock

Quantity

1

Base Price: ₹ 11,901.40

GST (18%): ₹ 2,142.252

Total Price: ₹ 14,043.652

Chemical Name or Material

8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Quantity

10 mg

Molecular Formula

C25H21N5O.2HCl

CAS

1032350-13-2

Target

Akt (Protein Kinase B) Inhibitors

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
200006992
Tocris Bioscience™ MK 2206 dihydrochloride
Fischer Scientific --
78-505-0
Tocris Bioscience™ MK 2206 dihydrochloride
Fischer Scientific ₹ 50,052.60
50-225-9120
Medchemexpress LLC HY-10358 200mg , MK-2206 (dihydrochloride) CAS:1032350-13-2 Purity:>98%
Medchemexpress LLC ₹ 40,427.10
50-190-4778
Apexbio Technology LLC MK-2206 dihydrochloride, 500mg. Cas: 1032350-13-2 MFCD: MFCD14584463. Akt1/2/3 inhibitor
Apexbio Technology LLC ₹ 1,28,340.00
NC1940643
Medchemexpress LLC 10 mM * 1 mL in DMSO, MK2206 | 1032350-13-2
Medchemexpress LLC ₹ 5,929.31
50-872-5
Selleck Chemical LLC MK-2206 2HCl 5mg 1032350-13-2
Selleck Chemical LLC ₹ 15,092.78
50-872-7
Selleck Chemical LLC MK-2206 2HCl 25mg 1032350-13-2
Selleck Chemical LLC ₹ 40,760.78
50-101-5869
AdipoGen MK-2206 dihydrochloride, 1032350-13-2, MFCD14584463, 1 mg
AdipoGen ₹ 7,477.94
NC1419665
Cayman Chemical MK-2206 (hydrochloride), 1032350-13-2, 10 mg
Cayman Chemical ₹ 10,429.76
NC1316862
Cayman Chemical MK-2206 (hydrochloride), 1032350-13-2, 1 mg
Cayman Chemical ₹ 4,483.34

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Description

  • MK 2206 dihydrochloride is a potent and selective allosteric Akt inhibitor (IC50 values are 5 nM, 12 nM, and 65 nM for Akt1, Akt2, and Akt3, respectively)
  • MK 2206 requires the Pleckstrin homology domain for its activity, and exhibits no inhibitory activity in a panel of 250 tested protein kinases
  • MK 2206 induces growth inhibition of different cancer cell lines (IC50 in the range 3.4 and 28.6 μmol/L) and enhances antitumor efficacy of a range of standard chemotherapeutics
  • It synergistically inhibits cell proliferation of human lung and breast cancer cells in combination with Erlotinib (Cat
  • No
  • 7194) by suppressing both the Ras/Erk and PI 3-K pathways in vitro and in vivo
  • MK 2206 can be used to block the IL-22 - Akt signaling pathway for studying paneth cell differentiation.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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Fischer Scientific

78-501-0

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Chemical Name or Material:
8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Quantity:
10 mg

Molecular Formula:
C25H21N5O.2HCl

CAS:
1032350-13-2

Target:
Akt (Protein Kinase B) Inhibitors

Purity:
0.98

Img

Fischer Scientific

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--


Chemical Name or Material:
8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Quantity:
50 mg

Molecular Formula:
C25H21N5O.2HCl

CAS:
1032350-13-2

Target:
Akt (Protein Kinase B) Inhibitors

Purity:
0.98

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Chemical Name or Material:
2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonyl fluoride

Quantity:
10 mg

Molecular Formula:
C13H11FN2O5S

CAS:
2803819-61-4

Target:
CRBN

Purity:
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eBioscience

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Chemical Name or Material:
__

Quantity:
100 μg

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__