76-591-0
Tocris Bioscience™ Verubecestat
Manufacturer: Fischer Scientific
CAS Number: 1286770-55-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 76-591-0-Each-of-1 | In Stock | ₹ 15,582.19 |
76-591-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,582.19
GST (18%): ₹ 2,804.794
Total Price: ₹ 18,386.984
Chemical Name or Material
N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity
10 mg
Molecular Formula
C17H17F2N5O3S
CAS
1286770-55-5
Target
Secretase Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Verubecestat | Fischer Scientific | -- | |
| | Tocris Bioscience™ Verubecestat | Fischer Scientific | ₹ 65,405.49 | |
 | Medchemexpress LLC HY-16759 100mg , Verubecestat CAS:1286770-55-5 Purity:>98% | Medchemexpress LLC | ₹ 40,427.10 | |
 | eMolecules Ambeed / (R)-N-(3-(3-Amino-25-dimethyl-11-dioxido-56-dihydro-2H-124-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide / 1mg / 534567618 / A262054 / / 1286770-55-5 / MFCD28963974 / 409.410 / C17H17F2N5O3S | eMolecules | ₹ 4,693.82 | |
 | 2-Pyridinecarboxamide, N-[3-[(5R)-3-amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro- | Aaron Chemicals LLC | ₹ 1,882.32 - ₹ 57,667.44 | |
 | 1286770-55-5 | Verubecestat Free Base | A2B Chem | ₹ 2,310.12 - ₹ 23,272.32 |
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Description
- Verubecestat is a high affinity and selective β-secretase 1 (BACE1) and its homolog BACE2 inhibitor (Ki of 2.2 nM and 0.38 nM respectively)
- It exhibits no inhibition of cathepsin D, cathepsin E, pepsin, or renin
- Verubecestat potently reduces Aβ40 formation in HEK293 APPSwe/Lon cells (IC50 = 2.1 nM)
- Verubecestat significantly lowers CSF and brain Aβ levels in rats
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity: 10 mg
Molecular Formula: C17H17F2N5O3S
CAS: 1286770-55-5
Target: Secretase Inhibitors
Purity: 0.98
Chemical Name or Material:
N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity:
10 mg
Molecular Formula:
C17H17F2N5O3S
CAS:
1286770-55-5
Target:
Secretase Inhibitors
Purity:
0.98
Chemical Name or Material: N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity: 50 mg
Molecular Formula: C17H17F2N5O3S
CAS: 1286770-55-5
Target: Secretase Inhibitors
Purity: 0.98
Chemical Name or Material:
N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity:
50 mg
Molecular Formula:
C17H17F2N5O3S
CAS:
1286770-55-5
Target:
Secretase Inhibitors
Purity:
0.98
Chemical Name or Material: __
Quantity: 1 mg
Molecular Formula: __
CAS: 897026-25-4
Target: __
Purity: 0.95
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Quantity:
1 mg
Molecular Formula:
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CAS:
897026-25-4
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Purity:
0.95
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CAS: __
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