77-811
Tocris Bioscience™ tri-GalNAc-C5-amine
Manufacturer: Tocris Bioscience™
CAS Number: 2098275-86-4
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Chemical Name or Material
N-[2-[[1-[2-[2-[2-[2-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]-1,1-bis[[[1-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-tr
Quantity
1 mg
Molecular Formula
C67H118N14O31
CAS
2098275-86-4
Target
ASGPR1
Related Products
Description
- tri-GalNAc-C5-amine is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; each molecule incorporates three ASGPR ligands with an alkylC5 linker and an amine group reactive handle ready for conjugation
- Upon binding to the ASGPR, tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis
- tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to hepatocytes
- Can be used to generate LYTACs, or labeled with dye for tissue imaging.
SAFETY INFORMATION
- Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
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Chemical Name or Material: N-[2-[[1-[2-[2-[2-[2-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]-1,1-bis[[[1-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-tr
Quantity: 1 mg
Molecular Formula: C67H118N14O31
CAS: 2098275-86-4
Target: ASGPR1
Chemical Name or Material:
N-[2-[[1-[2-[2-[2-[2-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]-1,1-bis[[[1-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-tr
Quantity:
1 mg
Molecular Formula:
C67H118N14O31
CAS:
2098275-86-4
Target:
ASGPR1
Chemical Name or Material: 1,6-Dihydrobenzo[1,2-d:4,5-d']bis([1,3]oxazine)-2,4,7,9-tetraone
Quantity: 10 mg
Molecular Formula: C10H4N2O6
CAS: __
Target: DNA, RNA and Protein Synthesis Compounds
Chemical Name or Material:
1,6-Dihydrobenzo[1,2-d:4,5-d']bis([1,3]oxazine)-2,4,7,9-tetraone
Quantity:
10 mg
Molecular Formula:
C10H4N2O6
CAS:
__
Target:
DNA, RNA and Protein Synthesis Compounds
Chemical Name or Material: 1,2-Dihydro-3,1-benzoxazine-2,4-dione
Quantity: 50 mg
Molecular Formula: C8H5NO3
CAS: 118-48-9
Target: DNA, RNA and Protein Synthesis Compounds
Chemical Name or Material:
1,2-Dihydro-3,1-benzoxazine-2,4-dione
Quantity:
50 mg
Molecular Formula:
C8H5NO3
CAS:
118-48-9
Target:
DNA, RNA and Protein Synthesis Compounds
Chemical Name or Material: pH QC Sample
Quantity: 250 mL
Molecular Formula: __
CAS: __
Target: __
Chemical Name or Material:
pH QC Sample
Quantity:
250 mL
Molecular Formula:
__
CAS:
__
Target:
__