50-052-60001
MilliporeSigma™ Calbiochem™ NOX Inhibitor VII, Thr101
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-052-60001-Each-of-1 | In Stock | ₹ 23,479.38 |
50-052-60001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,479.38
GST (18%): ₹ 4,226.288
Total Price: ₹ 27,705.668
Color
Light Brown
Target Proteins
blocks p22phox c-terminal PRD (proline-rich domain) and p47phox bis-SH3 interaction
Solubility
DMSO
Form
Powder
Description
98% by HPLC
Molecular Formula
C14H10FNOS
Content And Storage
Protect from light
Quantity
25 mg
Related Products
Description
- A cell-permeable, selenium-to-sulfur substituted Ebselen (Cat
- No
- 324483) derivative that exhibits similar NOX2 inhibitory activity as Ebselen by blocking p22 phox c-terminal PRD (proline-rich domain) and p47 phox bis -SH3 interaction
- Although less potent than Ebselen in cell-free p22 phox PRD-p47 phox bis -SH3 binding (IC 50 = 4 vs
- 0.3μM) and NOX2 activity (IC 50 = 4 vs
- 0.6μM) assays, Thr101 is more potent and NOX2-selective than Ebselen in cell-based assays (Thr101 IC 50 /Ebselen IC 50 = 0.3/0.5, 3/0.15, 8/no inhibition, 8/0.7μM, respectively, against NOX2, NOX1, NOX4, and NOX5) and exhibits no glutathione peroxidase activity
- Please note that the molecular weight for this compound is batch-specific due to variable water content
- Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight
- The molecular weight provided represents the baseline molecular weight without water.
Compare Similar Items
Show Difference
Color: Light Brown
Target Proteins: blocks p22phox c-terminal PRD (proline-rich domain) and p47phox bis-SH3 interaction
Solubility: DMSO
Form: Powder
Description: 98% by HPLC
Molecular Formula: C14H10FNOS
Content And Storage: Protect from light
Quantity: 25 mg
Color:
Light Brown
Target Proteins:
blocks p22phox c-terminal PRD (proline-rich domain) and p47phox bis-SH3 interaction
Solubility:
DMSO
Form:
Powder
Description:
98% by HPLC
Molecular Formula:
C14H10FNOS
Content And Storage:
Protect from light
Quantity:
25 mg
Color: __
Target Proteins: ASIC3
Solubility: Aqueous buffer
Form: Lyophilized
Description: 95% by HPLC
Molecular Formula: C196H280N54O61S6
Content And Storage: Protect from light
Quantity: 100 μg
Color:
__
Target Proteins:
ASIC3
Solubility:
Aqueous buffer
Form:
Lyophilized
Description:
95% by HPLC
Molecular Formula:
C196H280N54O61S6
Content And Storage:
Protect from light
Quantity:
100 μg
Color: __
Target Proteins: Major hubs involved in TLR signaling cascade
Solubility: __
Form: Solid
Description: __
Molecular Formula: __
Content And Storage: Hygroscopic, Protect from light
Quantity: 1 Each
Color:
__
Target Proteins:
Major hubs involved in TLR signaling cascade
Solubility:
__
Form:
Solid
Description:
__
Molecular Formula:
__
Content And Storage:
Hygroscopic, Protect from light
Quantity:
1 Each
Color: __
Target Proteins: __
Solubility: __
Form: __
Description: __
Molecular Formula: __
Content And Storage: __
Quantity: __
Color:
__
Target Proteins:
__
Solubility:
__
Form:
__
Description:
__
Molecular Formula:
__
Content And Storage:
__
Quantity:
__