50-831-70001
MilliporeSigma™ Calbiochem™ A740003
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-831-70001-Each-of-1 | In Stock | ₹ 16,732.00 |
50-831-70001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,732.00
GST (18%): ₹ 3,011.76
Total Price: ₹ 19,743.76
Color
Off-white
Target Proteins
P2X7
Solubility
Warm DMSO
Form
Powder
Description
98% by HPLC
Molecular Formula
C26H30N6O3
Content And Storage
Protect from light
Quantity
5 mg
Related Products
Description
- A highly potent, selective, competitive antagonist of P2X7 purinegic receptor (IC 50 = 18nM and 40 nM, respectively as measured by Bz-ATP-stimulated Ca2+ flux)
- Does not affect other P2 receptors even at 10μM concentrations
- Blocks agonist-evoked IL-1b release (IC 50 = 156nM) and pore formation (IC 50 = 92nM) in differentiated human THP-1 cells
- Also shown to reduce carrageenan and Freund′s adjuvant -induced thermal hyperalgesia (ED 50 = 38-54mg/kg, i.p) and neuropathic pain induced by chronic constriction injury (CIC) of the sciatic nerve.
Compare Similar Items
Show Difference
Color: Off-white
Target Proteins: P2X7
Solubility: Warm DMSO
Form: Powder
Description: 98% by HPLC
Molecular Formula: C26H30N6O3
Content And Storage: Protect from light
Quantity: 5 mg
Color:
Off-white
Target Proteins:
P2X7
Solubility:
Warm DMSO
Form:
Powder
Description:
98% by HPLC
Molecular Formula:
C26H30N6O3
Content And Storage:
Protect from light
Quantity:
5 mg
Color: __
Target Proteins: __
Solubility: __
Form: __
Description: __
Molecular Formula: __
Content And Storage: __
Quantity: __
Color:
__
Target Proteins:
__
Solubility:
__
Form:
__
Description:
__
Molecular Formula:
__
Content And Storage:
__
Quantity:
__
Color: White
Target Proteins: SHIP2
Solubility: DMSO
Form: Solid
Description: 98% by HPLC
Molecular Formula: C20H15ClF2N2O2
Content And Storage: Protect from light
Quantity: 10 mg
Color:
White
Target Proteins:
SHIP2
Solubility:
DMSO
Form:
Solid
Description:
98% by HPLC
Molecular Formula:
C20H15ClF2N2O2
Content And Storage:
Protect from light
Quantity:
10 mg
Color: White
Target Proteins: EED (embryonic ectoderm development) - EZH2
Solubility: H2O
Form: Powder
Description: 95% by HPLC
Molecular Formula: C155H256N48O40·6TFA·14H2O
Content And Storage: Protect from light
Quantity: 2 mg
Color:
White
Target Proteins:
EED (embryonic ectoderm development) - EZH2
Solubility:
H2O
Form:
Powder
Description:
95% by HPLC
Molecular Formula:
C155H256N48O40·6TFA·14H2O
Content And Storage:
Protect from light
Quantity:
2 mg