SML0067
IOX1
≥97% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 5852-78-8
Synonym(S): 5-Carboxy-8-hydroxyquinoline, 8-Hydroxy-5-quinolinecarboxylic acid
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML0067-5-MG | In Stock | ₹ 14,483.85 |
| 25 MG | SML0067-25-MG | In Stock | ₹ 39,771.05 |
SML0067 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 14,483.85
GST (18%): ₹ 2,607.093
Total Price: ₹ 17,090.943
Assay
≥97% (HPLC)
form
powder
color
white to brown
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC(=O)c1ccc(O)c2ncccc12
InChI
1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
InChI key
JGRPKOGHYBAVMW-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ JMJD2 Inhibitor, 5-carboxy-8HQ | MilliporeSigma™ | ₹ 19,079.88 | |
 | eMolecules Ambeed / 8-Hydroxyquinoline-5-carboxylic acid / 1mg / 534566909 / A170634 / / 5852-78-8 / MFCD18417145 / 189.170 / C10H7NO3 | eMolecules | ₹ 2,854.28 | |
 | Sigma Aldrich Fine Chemicals Biosciences IOX1 >=97% (HPLC) | 5852-78-8 | MFCD18417145 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 52,773.41 | |
| | Sigma Aldrich Fine Chemicals Biosciences IOX1 >=97% (HPLC) | 5852-78-8 | MFCD18417145 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 13,521.05 | |
 | Medchemexpress LLC HY-12304 5mg Medchemexpress, IOX1 CAS:5852-78-8 Purity:>98% | Medchemexpress LLC | ₹ 6,917.53 | |
 | Selleck Chemical LLC IOX1 10mg 5852-78-8 | Selleck Chemical LLC | ₹ 15,092.78 | |
 | 5852-78-8 | 8-Hydroxyquinoline-5-carboxylic acid | A2B Chem | ₹ 2,652.36 - ₹ 12,577.32 |
Related Products
Description
- Application: IOX1 has been used:To eliminate viral latency in latent viruses in order to sensitize the viral infections to antiviral therapy.[1]In histone lysine demethylase 4A (KDM4A) inhibition, to serve as a unique strategy to decrease hypoxia-inducible factors signalling.[2]to restore oncogene-induced senescence in wild-type mouse embryo fibroblasts.[3]
- Biochem/physiol Actions: IOX1 (5-Carboxy-8-hydroxyquinoline) is a broad spectrum inhibitor of 2-oxoglutarate (2OG) oxygenases, including Jumonji C domain (JmjC) demethylases. It is useful for the study of histone demethylation and hypoxic sensing and results in translocation of active site iron on the 2OG oxygenases. For full characterization details, please visit the IOX1 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
- Features and Benefits: IOX1 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Assay: ≥97% (HPLC)
form: powder
color: white to brown
solubility: DMSO: 10 mg/mL, clear
storage temp.: 2-8°C
SMILES string: OC(=O)c1ccc(O)c2ncccc12
InChI: 1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
InChI key: JGRPKOGHYBAVMW-UHFFFAOYSA-N
Assay:
≥97% (HPLC)
form:
powder
color:
white to brown
solubility:
DMSO: 10 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
OC(=O)c1ccc(O)c2ncccc12
InChI:
1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
InChI key:
JGRPKOGHYBAVMW-UHFFFAOYSA-N
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: ≥10 mg/mL
storage temp.: 2-8°C
SMILES string: COc1ccccc1S(=O)(=O)Nc2ccc3NC(=O)N(C)Cc3c2
InChI: 1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20)
InChI key: TXZPMHLMPKIUGK-UHFFFAOYSA-N
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: ≥10 mg/mL
storage temp.:
2-8°C
SMILES string:
COc1ccccc1S(=O)(=O)Nc2ccc3NC(=O)N(C)Cc3c2
InChI:
1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20)
InChI key:
TXZPMHLMPKIUGK-UHFFFAOYSA-N
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 5 mg/mL, clear
storage temp.: −20°C
SMILES string: __
InChI: __
InChI key: __
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 5 mg/mL, clear
storage temp.:
−20°C
SMILES string:
__
InChI:
__
InChI key:
__
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 5 mg/mL, clear (warmed)
storage temp.: 2-8°C
SMILES string: OC(C1=C(N2CC3=CC=CC=C3)C=CC=C1)=C(C(NCC(O)=O)=O)C2=O
InChI: 1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
InChI key: CAOSCCRYLYQBES-UHFFFAOYSA-N
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 5 mg/mL, clear (warmed)
storage temp.:
2-8°C
SMILES string:
OC(C1=C(N2CC3=CC=CC=C3)C=CC=C1)=C(C(NCC(O)=O)=O)C2=O
InChI:
1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
InChI key:
CAOSCCRYLYQBES-UHFFFAOYSA-N