SAB4200621

Monoclonal Anti-NG2/CSPG4 antibody produced in mouse

clone 2164B6, purified from hybridoma cell culture

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
100 μL SAB4200621-100-μL In Stock ₹ 56,543.40

SAB4200621 - 100 μL

₹ 56,543.40

In Stock

Quantity

1

Base Price: ₹ 56,543.40

GST (18%): ₹ 10,177.812

Total Price: ₹ 66,721.212

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2164B6, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

~1 mg/mL

technique(s)

flow cytometry: 2.5-5 μg/test using SK-Mel-28 cells.immunofluorescence: 2.5-5 μg/mL using A375 cells.

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Description

  • General description: Nerve/glial antigen 2 (NG2), a high molecular mass melanoma- associated antigen (HMW-MAA), is a large integral membrane, cell surface type I transmembrane protein that is covalently modified with chondroitin sulfate glycosaminoglycan.
  • Immunogen: a recombinant extracellular portion of human NG2 proteoglycan
  • Application: Monoclonal Anti-NG2/CSPG4 antibody produced in mouse used in flow cytometry and immunocytochemistry.
  • Biochem/physiol Actions: Nerve/glial antigen 2 (NG2) plays a central role in linking multiple oncogenic pathways required for malignant progression. NG2 expression in radial growth phase (RGP) human melanomas enables migration, protease activation and epithelial to mesenchymal transition, which is important in primary tumors for facilitating progression from a radial to vertical growth phase phenotype. It regulates sustained, high-level activation of key survival and growth pathways, integrin-regulated focal adhesion kinase (FAK), extracellular signal-regulated kinases 1 and 2 (ERK 1,2) and phosphoinositide 3-kinase (PI3K)/AKT pathways.
  • Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
  • Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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SAB4200621

clone 2164B6, purified from hybrido...


biological source:
mouse

Quality Level:
200

conjugate:
unconjugated

antibody form:
purified immunoglobulin

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primary antibodies

clone:
2164B6, monoclonal

form:
buffered aqueous solution

species reactivity:
human

concentration:
~1 mg/mL

technique(s):
flow cytometry: 2.5-5 μg/test using SK-Mel-28 cells.immunofluorescence: 2.5-5 μg/mL using A375 cells.

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mouse

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buffered aqueous solution

species reactivity:
bovine, mouse, rat, monkey, human, canine

concentration:
~1 mg/mL

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