14-079-137
CD79a Monoclonal Antibody (24C2.5), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-079-137-Each-of-1 | In Stock | ₹ 1,17,388.32 |
14-079-137 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,388.32
GST (18%): ₹ 21,129.898
Total Price: ₹ 1,38,518.218
Antigen
CD79a
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P11911, P11912
Gene Symbols
CD79A
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12518, 973
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Clone
24C2.5
Conjugate
Unconjugated
Gene
CD79A
Gene Alias
B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: This 24C2.5 monoclonal antibody reacts with the intracellular tail of mouse CD79a (also known as Ig alpha or mb-1), a signaling component of the B cell receptor (BCR)
- CD79a heterodimerizes with CD79b (Ig beta, B29), and together with surface Ig, make up the BCR
- Both CD79 subunits consist of a single extracellular Ig domain, a transmembrane domain, and an intracellular signaling domain
- CD79a is expressed almost exclusively on B cells, as well as in most B lineage acute lymphoblastic leukemias
- The cytoplasmic domain of CD79a contains immunoreceptor tyrosine-based activation motifs (ITAMs), which constitute the signal transducing portions of the BCR
- Tyrosine phosphorylation of these ITAMs by Syk and Lyn initiates numerous signaling cascades, resulting in B cell activation, proliferation, and differentiation
- Applications Reported: This 24C2.5 antibody has been reported for use in immunoblotting (WB)
- Applications Tested: This 24C2.5 antibody has been tested by western blot of reduced mouse spleen lysates
- This can be used at 1-10 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide
- CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor
- CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component
- CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas
- It is not present in myeloid or T cell lines
- Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
Compare Similar Items
Show Difference
Antigen: CD79a
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P11911, P11912
Gene Symbols: CD79A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12518, 973
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Clone: 24C2.5
Conjugate: Unconjugated
Gene: CD79A
Gene Alias: B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD79a
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P11911, P11912
Gene Symbols:
CD79A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12518, 973
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Clone:
24C2.5
Conjugate:
Unconjugated
Gene:
CD79A
Gene Alias:
B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD79b
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P40259
Gene Symbols: Cd79b
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 974
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: CB3-1
Conjugate: Unconjugated
Gene: Cd79b
Gene Alias: AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD79b
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P40259
Gene Symbols:
Cd79b
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
974
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
CB3-1
Conjugate:
Unconjugated
Gene:
Cd79b
Gene Alias:
AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD79b
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P40259
Gene Symbols: Cd79b
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 974
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: CB3-1
Conjugate: Unconjugated
Gene: Cd79b
Gene Alias: AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Host Species: Mouse
Quantity: 10 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD79b
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P40259
Gene Symbols:
Cd79b
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
974
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
CB3-1
Conjugate:
Unconjugated
Gene:
Cd79b
Gene Alias:
AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Host Species:
Mouse
Quantity:
10 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: __
Classification: __
Concentration: __
Formulation: __
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Quantity: 5 Pack
Primary or Secondary: __
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Product Type: Cryo Storage Box
Isotype: __
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Quantity:
5 Pack
Primary or Secondary:
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Product Type:
Cryo Storage Box
Isotype:
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