14-976-937

Insulin Monoclonal Antibody (ICBTACLS), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 14-976-937-Each-of-1 In Stock ₹ 1,17,901.68

14-976-937 - Each of 1

₹ 1,17,901.68

In Stock

Quantity

1

Base Price: ₹ 1,17,901.68

GST (18%): ₹ 21,222.302

Total Price: ₹ 1,39,123.982

Antigen

Insulin

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P01308, P01322, P01323, P01325, P01326

Gene Symbols

INS, Ins1, Ins2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16333, 16334, 24505, 24506, 3630

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

ICBTACLS

Conjugate

Unconjugated

Gene

INS

Gene Alias

AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin

Host Species

Mouse

Quantity

2 mg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • This ICBTACLS MAb reacts with the hormone insulin, responsible for regulation of carbohydrate and fat metabolism
  • Blood glucose levels are maintained by insulin
  • Insulin secretion from pancreatic beta-cells within the islets of Langerhans results in uptake of excess glucose from the blood into organs and its storage in the form of glycogen
  • Patients with type 1 diabetes have an autoimmune destruction of insulin-producing beta-cells in the pancreas, resulting in insulin deficiency and elevated levels of blood glucose
  • Patients with type 2 diabetes have insulin resistance where insulin becomes less effective at reducing the amount of blood glucose
  • Insulin is also important for proper endothelial cell function in with respect to vascular elasticity in response to changing blood pressure and plays a role in cognition, learning, and memory
  • The ICBTACLS antibody recognizes human, mouse, and rat insulin
  • Insulin is a peptide hormone secreted by beta cells of the pancreatic islets
  • It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions
  • It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids
  • Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin
  • Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide
  • Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population
  • Insulin is also present in tumors of b-cell origin such as insulinoma.

Compare Similar Items

Show Difference

Img

Invitrogen

14-976-937

--


Antigen:
Insulin

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01308, P01322, P01323, P01325, P01326

Gene Symbols:
INS, Ins1, Ins2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16333, 16334, 24505, 24506, 3630

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ICBTACLS

Conjugate:
Unconjugated

Gene:
INS

Gene Alias:
AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

14-977-137

--


Antigen:
Collagen X

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q03692, Q05306

Gene Symbols:
COL10A1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100856711, 106026924, 12813, 1300, 25681, 448809

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
X53

Conjugate:
Unconjugated

Gene:
COL10A1

Gene Alias:
Col10; COL10A1; Col10a-1; Collagen alpha-1(X) chain; collagen type X alpha 1 chain; collagen X, alpha-1 polypeptide; collagen, type X, alpha 1; collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia); pro alpha 1; procollagen, type X, alpha 1; Schmid metaphyseal chondrodysplasia; type X collagen; type X collagen, alpha 1

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Canine, Guinea Pig, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

14-977-280

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Antigen:
Dynein

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% Sodium Azide; pH 7.2

Gene Accession No.:
P61285, P63167, P63168, P63170, Q3MHR3, Q78P75, Q96FJ2, Q9D0M5

Gene Symbols:
DYNLL1, DYNLL2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100157773, 100512860, 101118902, 101121274, 140734, 140735, 404151, 540369, 56455, 58945, 68097, 8655

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
74.1

Conjugate:
Unconjugated

Gene:
DYNLL1

Gene Alias:
1700064A15Rik; 6720463E02Rik; 8 kDa dynein light chain; 8 kDa dynein light chain b; 8kD LC; 8kDa LC; 8kDLC; C87222; CDLC2; cytoplasmic dynein light polypeptide; cytoplasmic dynein light polypeptide 1; cytoplasmic light-chain dynein; cytosolic DH IC-1; DLC1; Dlc2; DLC8; DLC8b; DNCL1; DNCL1B; Dnclc1; dynein LC8; dynein light chain 1, cytoplasmic; Dynein light chain 2, cytoplasmic; dynein light chain LC8-type 1; Dynein light chain LC8-type 2; dynein light chain-2; dynein, cytoplasmic, light chain 1; dynein, cytoplasmic, light peptide; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; dynein, light chain, LC8-type 2; DYNLL1; DYNLL2; HDLC1; LC8; LC8; PIN; LC8a; LOC540369 protein; mPIN; PIN; Protein inhibitor of neuronal nitric oxide synthase; protein inhibitor of nitric oxide synthase; radial spoke 22 homolog; RSPH22; similar to cytoplasmic dynein light chain 1

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Drosophila, Human, Mouse, Ovine, Porcine, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Fischer Scientific

14-977-337

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Antigen:
SOX11

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P35716

Gene Symbols:
SOX11

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6664

Content And Storage:
4° C

Form:
Liquid

Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SOX11-C1

Conjugate:
Unconjugated

Gene:
SOX11

Gene Alias:
1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox11; Sox-11; SRY; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-box transcription factor 11; SRY-related HMG-box gene 11; transcription factor SOX-11

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ