17-932-282
PLZF Monoclonal Antibody (9E12), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 17-932-282-Each-of-1 | In Stock | ₹ 29,518.20 |
17-932-282 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,518.20
GST (18%): ₹ 5,313.276
Total Price: ₹ 34,831.476
Antigen
PLZF
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q05516
Gene Symbols
ZBTB16
Immunogen
PLFZ peptide
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry
Clone
9E12
Conjugate
APC
Gene
ZBTB16
Gene Alias
AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145
Host Species
Armenian Hamster
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
235320, 7704
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- This 9E12 monoclonal antibody reacts with human and mouse promyelocytic leukemia zinc finger (PLZF), a member of the BTB-POZ family of transcription factors
- Expression of this transcriptional repressor in immune cells differs between mice and humans
- In mice, PLZF is highly expressed in immature CD1d-resricted NKT2 and NKT1 cells, and a subset of gamma delta (Vg1.1+Vd6.3+) T cells
- Studies have also demonstrated expression of PLZF in non-invariant CD1d-restricted T cells, as well as non-CD1d-restricted innate T cells
- In humans, PLZF is expressed in NK cells, gamma delta T cells, as well as CD4 and CD8+ T cells
- PLZF is also expressed in MR1-specific mucosal-associated invariant T cells, as well as in MHC Class II-restricted T cells that develop via a thymocyte-thymocyte interaction in humans
- PLZF is expressed by innate lymphoid cells and its progenitor cells
- PLZF exists as a homodimer or in complex with PLZP, and has been shown to be involved in the development of NKT cells, NK cell function, cellular quiescence, growth suppression, and maintece of homeostatis
- Finally, PLZF has been shown to inhibit gene expression induced by retinoic acid receptor
- This 9E12 antibody stains mouse thymocytes brighter than Mags.21F7
- This 9E12 antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcription Factor Staining Buffer Set (cat
- 00-5523) and protocol
- This can be used at less than or equal to 0
- This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus
- This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase
- Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL)
- Alternate transcriptional splice variants have been characterized.
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Antigen: PLZF
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q05516
Gene Symbols: ZBTB16
Immunogen: PLFZ peptide
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry
Clone: 9E12
Conjugate: APC
Gene: ZBTB16
Gene Alias: AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145
Host Species: Armenian Hamster
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 235320, 7704
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
PLZF
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q05516
Gene Symbols:
ZBTB16
Immunogen:
PLFZ peptide
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry
Clone:
9E12
Conjugate:
APC
Gene:
ZBTB16
Gene Alias:
AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145
Host Species:
Armenian Hamster
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
235320, 7704
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
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