15-988-342
HELIOS Monoclonal Antibody (22F6), PE-Cyanine5, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 15-988-342-Each-of-1 | In Stock | ₹ 36,534.12 |
15-988-342 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,534.12
GST (18%): ₹ 6,576.142
Total Price: ₹ 43,110.262
Antigen
HELIOS
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P81183, Q9UKS7
Gene Symbols
IKZF2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22779, 22807, 488510
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
22F6
Conjugate
PE-Cyanine5
Gene
IKZF2
Gene Alias
A730095J18Rik, ANF1A2, Helios, IKAROS family zinc finger 2, IKAROS family zinc finger 2 (Helios), ikaros family zinc finger protein 2, Ikzf2, Zfpn1a2, zinc finger DNA binding protein Helios, zinc finger protein Helios, zinc finger protein, subfamily 1A, 2 (Helios), ZNF1A2, Znfn1a2
Host Species
Armenian Hamster
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description: This 22F6 monoclonal antibody reacts with human, mouse and canine Helios
- Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros
- It is expressed in hematopoietic stem cells in both the embryo and adult mice
- While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells
- Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription
- Eight isoforms of Helios exist, some of which possess a domit-negative function that has also been found to be upregulated in lymphoid maligcies, including T-acute lymphoblastic leukemia
- 22F6 has been reported to cross react with rat Helios
- Applications Reported: This 22F6 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 22F6 antibody has been pre-diluted and tested by flow cytometric analysis of mouse lymph node cells using the Foxp3/Transcription Factor Staining Buffer Set (Product No
- 00-5523-00) and protocol
- Please refer to Staining Intracellular Antigens for Flow Cytometry, Protocol B: One step protocol for intracellular (nuclear) proteins located at www.thermofisher.com/flowprotocols
- This may be used at 5 μL (0.06 μg) per test
- This gene encodes a member of the Ikaros family of zinc-finger proteins
- Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development
- This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development
- Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Compare Similar Items
Show Difference
Antigen: HELIOS
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P81183, Q9UKS7
Gene Symbols: IKZF2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22779, 22807, 488510
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 22F6
Conjugate: PE-Cyanine5
Gene: IKZF2
Gene Alias: A730095J18Rik, ANF1A2, Helios, IKAROS family zinc finger 2, IKAROS family zinc finger 2 (Helios), ikaros family zinc finger protein 2, Ikzf2, Zfpn1a2, zinc finger DNA binding protein Helios, zinc finger protein Helios, zinc finger protein, subfamily 1A, 2 (Helios), ZNF1A2, Znfn1a2
Host Species: Armenian Hamster
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HELIOS
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P81183, Q9UKS7
Gene Symbols:
IKZF2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22779, 22807, 488510
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
22F6
Conjugate:
PE-Cyanine5
Gene:
IKZF2
Gene Alias:
A730095J18Rik, ANF1A2, Helios, IKAROS family zinc finger 2, IKAROS family zinc finger 2 (Helios), ikaros family zinc finger protein 2, Ikzf2, Zfpn1a2, zinc finger DNA binding protein Helios, zinc finger protein Helios, zinc finger protein, subfamily 1A, 2 (Helios), ZNF1A2, Znfn1a2
Host Species:
Armenian Hamster
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Gata-3
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P23771, P23772
Gene Symbols: GATA3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14462, 2625, 713840, 733631
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TWAJ
Conjugate: PE-Cyanine5
Gene: GATA3
Gene Alias: EGK_19445, GATA binding factor-3, GATA binding protein 3, GATA binding protein-3, GATA3, Gata-3, GATA-binding factor 3, GATA-binding protein 3, HDR, HDRS, jal, MGC2346, MGC5199, MGC5445, Trans-acting T-cell-specific transcription factor GATA-3, Transacting T-cell-specific transcription factor GATA-3
Host Species: Rat
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Gata-3
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P23771, P23772
Gene Symbols:
GATA3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14462, 2625, 713840, 733631
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TWAJ
Conjugate:
PE-Cyanine5
Gene:
GATA3
Gene Alias:
EGK_19445, GATA binding factor-3, GATA binding protein 3, GATA binding protein-3, GATA3, Gata-3, GATA-binding factor 3, GATA-binding protein 3, HDR, HDRS, jal, MGC2346, MGC5199, MGC5445, Trans-acting T-cell-specific transcription factor GATA-3, Transacting T-cell-specific transcription factor GATA-3
Host Species:
Rat
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: TCR alpha/beta
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P01848, P04435, P0DSE1
Gene Symbols: TRA, TRAC, TRB, TRBV7-9
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 28589, 28755, 6955, 6957
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: IP26
Conjugate: PE-Cyanine5
Gene: TRAC
Gene Alias: FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
TCR alpha/beta
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P01848, P04435, P0DSE1
Gene Symbols:
TRA, TRAC, TRB, TRBV7-9
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
28589, 28755, 6955, 6957
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
IP26
Conjugate:
PE-Cyanine5
Gene:
TRAC
Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__