14-578-937
Aiolos Monoclonal Antibody (8B2), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-578-937-Each-of-1 | In Stock | ₹ 1,17,388.32 |
14-578-937 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,388.32
GST (18%): ₹ 21,129.898
Total Price: ₹ 1,38,518.218
Antigen
Aiolos
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O08900
Gene Symbols
Ikzf3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22780
Content And Storage
4° C
Form
Liquid
Applications
Western Blot
Clone
8B2
Conjugate
Unconjugated
Gene
Ikzf3
Gene Alias
5830411O07Rik; AIO; AIOLOS; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); ikaros family zinc finger protein 3; Ikzf3; Zfpn1a3; zinc finger DNA binding protein Aiolos; zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); Znfn1a3
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: This 8B2 monoclonal antibody reacts with mouse Aiolos, a 58-kDa member of the Ikaros family of zinc finger transcription factors
- Expression of Aiolos is restricted to the lymphoid lineage, with B cells exhibiting the highest levels of expression, followed by NK and T cells
- Studies demonstrate that Aiolos forms homodimers or heterodimerizes with Ikaros proteins
- Moreover, Aiolos exhibits tyrosine phosphorylation and nuclear localization in response to IL-2 stimulation in T cells
- Aiolos plays a role in IL-2-mediated anti-apoptosis by controlling Bcl-2 expression
- Finally, Aiolos is involved in B cell development, with upregulation of this transcription factor observed at the pre-BI to pre-BII transition in response to pre-B cell receptor signaling
- Applications Reported: This 8B2 antibody has been reported for use in immunoblotting/western blotting
- Applications Tested: This 8B2 antibody has been tested by immunoblotting of reduced cell lysate prepared from mouse splenocytes
- This can be used at less than or equal to 5 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- This gene encodes a member of the Ikaros family of zinc-finger proteins
- Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development
- This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation
- Both Ikaros and Aiolos can participate in chromatin remodeling
- Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers
- At least six alternative transcripts encoding different isoforms have been described.
Compare Similar Items
Show Difference
Antigen: Aiolos
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O08900
Gene Symbols: Ikzf3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22780
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Clone: 8B2
Conjugate: Unconjugated
Gene: Ikzf3
Gene Alias: 5830411O07Rik; AIO; AIOLOS; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); ikaros family zinc finger protein 3; Ikzf3; Zfpn1a3; zinc finger DNA binding protein Aiolos; zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); Znfn1a3
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Aiolos
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O08900
Gene Symbols:
Ikzf3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22780
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Clone:
8B2
Conjugate:
Unconjugated
Gene:
Ikzf3
Gene Alias:
5830411O07Rik; AIO; AIOLOS; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); ikaros family zinc finger protein 3; Ikzf3; Zfpn1a3; zinc finger DNA binding protein Aiolos; zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); Znfn1a3
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: T-bet
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9JKD8, Q9UL17
Gene Symbols: Tbx21
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 30009, 303496, 57765
Content And Storage: 4° C
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: eBio39D (39D, 3-9D)
Conjugate: Unconjugated
Gene: Tbx21
Gene Alias: HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
T-bet
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9JKD8, Q9UL17
Gene Symbols:
Tbx21
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
30009, 303496, 57765
Content And Storage:
4° C
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
eBio39D (39D, 3-9D)
Conjugate:
Unconjugated
Gene:
Tbx21
Gene Alias:
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD365 (Tim-1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q5QNS5
Gene Symbols: Havcr1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 171283
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: RMT1-4
Conjugate: Unconjugated
Gene: Havcr1
Gene Alias: AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species: Rat
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD365 (Tim-1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q5QNS5
Gene Symbols:
Havcr1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
171283
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RMT1-4
Conjugate:
Unconjugated
Gene:
Havcr1
Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species:
Rat
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD365 (Tim-1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q5QNS5
Gene Symbols: Havcr1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 171283
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: RMT1-4
Conjugate: Unconjugated
Gene: Havcr1
Gene Alias: AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD365 (Tim-1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q5QNS5
Gene Symbols:
Havcr1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
171283
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RMT1-4
Conjugate:
Unconjugated
Gene:
Havcr1
Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ