50-112-9068

Integrin beta 7 Monoclonal Antibody (FIB504), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 50-112-9068-Each In Stock ₹ 28,547.09

50-112-9068 - Each

₹ 28,547.09

In Stock

Quantity

1

Base Price: ₹ 28,547.09

GST (18%): ₹ 5,138.476

Total Price: ₹ 33,685.566

Antigen

Integrin beta 7

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P26010, P26011

Gene Symbols

ITGB7

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16421, 3695

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

FIB504

Conjugate

PE-Cyanine7

Gene

ITGB7

Gene Alias

Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen

Host Species

Rat

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: The FIB504 monoclonal antibody reacts with human and mouse integrin beta 7
  • Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes
  • It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes
  • Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324)
  • Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response
  • The FIB504 antibody has been reported to have blocking activity
  • Applications Reported: This FIB504 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This FIB504 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
  • Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes
  • It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes
  • Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324)
  • Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

Compare Similar Items

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Invitrogen

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Antigen:
Integrin beta 7

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P26010, P26011

Gene Symbols:
ITGB7

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16421, 3695

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
FIB504

Conjugate:
PE-Cyanine7

Gene:
ITGB7

Gene Alias:
Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen

Host Species:
Rat

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Antigen:
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Classification:
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Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O95936

Gene Symbols:
Eomes

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100622125, 8320

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
WD1928

Conjugate:
PerCP-eFluor 710

Gene:
Eomes

Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Product Type:
Antibody

Isotype:
IgG1 κ

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Antigen:
NKG2AB6

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
0

Gene Symbols:
Klrc1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16641

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
16a11

Conjugate:
PerCP-eFluor 710

Gene:
Klrc1

Gene Alias:
CD159 antigen-like family member A; CD159A; C-lectin type II protein; Cluster of Differentiation 159a; killer cell lectin like receptor C1; killer cell lectin-like receptor subfamily C, member 1; Klrc1; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2; NKG2-1/B activating NK receptor; NKG2A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; rNKG2A

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

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Classification:
Monoclonal

Concentration:
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Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
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Gene Symbols:
Pdcd1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
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Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
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Applications:
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Clone:
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Gene:
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Gene Alias:
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Host Species:
Armenian Hamster

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG