14-586-737

Integrin beta 7 Monoclonal Antibody (FIB504), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 14-586-737-Each-of-1 In Stock ₹ 1,17,388.32

14-586-737 - Each of 1

₹ 1,17,388.32

In Stock

Quantity

1

Base Price: ₹ 1,17,388.32

GST (18%): ₹ 21,129.898

Total Price: ₹ 1,38,518.218

Antigen

Integrin beta 7

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P26010, P26011

Gene Symbols

ITGB7

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16421, 3695

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Functional Assay

Clone

FIB504

Conjugate

Unconjugated

Gene

ITGB7

Gene Alias

Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen

Host Species

Rat

Quantity

2 mg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description The FIB504 MAb reacts with human and mouse integrin beta 7
  • Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes
  • It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes
  • Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324)
  • Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response
  • The FIB504 antibody has been reported to have blocking activity
  • Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes
  • It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes
  • Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324)
  • Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

Compare Similar Items

Show Difference

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Invitrogen

14-586-737

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Antigen:
Integrin beta 7

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P26010, P26011

Gene Symbols:
ITGB7

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16421, 3695

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay

Clone:
FIB504

Conjugate:
Unconjugated

Gene:
ITGB7

Gene Alias:
Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen

Host Species:
Rat

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

14-587-937

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Antigen:
CD314 (NKG2D)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P26718

Gene Symbols:
Klrk1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22914

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Neutralization

Clone:
5C6

Conjugate:
Unconjugated

Gene:
Klrk1

Gene Alias:
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

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Invitrogen

14-588-637

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Antigen:
Ly-49H

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q60682

Gene Symbols:
Klra8

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16639

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation

Clone:
3D10

Conjugate:
Unconjugated

Gene:
Klra8

Gene Alias:
Cmv1; Cmv-1; cytomegalovirus resistance 1; killer cell lectin-like receptor 8; killer cell lectin-like receptor, subfamily A, member 8; Klra8; Ly49H; Ly-49h; Ly49-h; Ly49u<129>; Lymphocyte antigen 49h; T-cell surface glycoprotein Ly-49H

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
CD249 (BP-1)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P16406

Gene Symbols:
Enpep

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13809

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Clone:
6C3

Conjugate:
Unconjugated

Gene:
Enpep

Gene Alias:
6030431M22Rik; Aminopeptidase A; aminopeptidase-A; APA; AP-A; BP1; Bp-1/6C3; BP-1/6C3 antigen; CD249; differentiation antigen gp160; EAP; ENPEP; Glutamyl aminopeptidase; glutamyl aminopeptidase (aminopeptidase A); gp160; Ly51; Ly-51

Host Species:
Rat

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ